Small Business Innovation Research (SBIR) Small Business Technology Transfer (STTR)


Need funding for your technology idea? Talk to HHS!

Small businesses are encouraged to submit their technology ideas to HHS for funding consideration. Researcher-initiated ideas are proposed via the SBIR and STTR Omnibus grant solicitations (also called funding opportunity announcements or FOAs). Applicants should speak with an HHS SBIR/STTR program manager BEFORE submitting an application. Program managers will discuss the Institute or Center (IC)’s interest in the proposed technology and can offer application-specific advice.

NIH Matchmaker can be used to conduct keyword searches of a particular topic area to identify ICs that have previously funded research in that area. Applicants can also search the 2016 Program Descriptions and Research Topics document to identify priority research areas of ICs, or email for an SBIR/STTR program manager referral. Applicants should send program managers a brief abstract or overview of their technology at least one month before the SBIR/STTR standard deadline

The Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA) and the Administration for Children and Families (ACF) also participate in the HHS Omnibus SBIR solicitation.

Applicants may also apply via the SBIR/STTR targeted grant solicitations, and the annual HHS SBIR contract. The targeted SBIR/STTR grant solicitations are focused on specific research areas, and the HHS SBIR contract clearly requests certain types of technologies. View the Apply page to learn more about the difference between grants and contracts, and the Application Types page to learn about different funding options for small businesses. 

For more information about the budget, please view our Budget FAQs and the Fiscal Year 2016 SBA approved topics for budget waivers.


Submit Your Application

Use the SF424 (R&R) SBIR/STTR Application Guide (Version D), and the Annotated SF424 (R&R) SBIR/STTR Form Set (FORMS-D) for step-by-step instructions on how to complete the application. Be mindful that the electronic submission process for HHS SBIR and STTR grants is multi-step, and can take six to eight weeks to complete the five registrations required prior to submission.


2016 SBIR and STTR Omnibus Grant Solicitations for the NIH, CDC, FDA and ACF

Contracts iconNIH SBIR/STTR Grant Forms

Standard Due Dates:

Calendar icon January 5 
Calendar icon April 5
Calendar icon September 5



The NIH SBIR Direct to Phase II Pilot Solicitations will expire soon. Please see the dates below for expiration dates.

FOA Last Due Date
PAR-14-088 Jan 5, 2017
PAR-14-265 (NINDS only) Jan 5, 2017
PAR-15-288 Apr 5, 2017
PAR-16-017 Jan 11, 2017 (AIDS only)
NIH SBIR Direct to Phase II Pilot Solicitation/s

Standard Due Dates:

Calendar icon January 5
Calendar icon  April 5 
Calendar icon September 5 



Targeted SBIR/STTR Solicitations


R&D Contract Solicitation:
SBIR Phase I, Fast-Track, Direct to Phase II Contract Solicitation, PHS 2017-1


The last due date for both CRP solicitations (PAR-16-026 & PAR-16-027) will be Apr 5, 2017.

Commercialization Readiness Pilot (CRP) Program Solicitations

PAR-16-026 (Technical Assistance)

PAR-16-027 (Technical Assistance and Late Stage Development)

Standard Due Dates:

Calendar icon January 5 
Calendar icon April 5
Calendar icon September 5