Special Announcements for Small Business Research Opportunities

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The SBIR/STTR Program

Targeted SBIR/STTR Funding Announcements

Receipt dates for the following Program Announcements (PAs) and Request for Applications (RFAs) may vary. See the NIH Guide for Grants and Contracts for all NIH RFA and PA announcements.

SBIR and STTR Omnibus Solicitations (Parent Announcements)

SBIR Omnibus/Parent Clinical Trial Not Allowed Funding Opportunity Announcement (PA-19-272)

STTR Omnibus/Parent Clinical Trial Not Allowed Funding Opportunity Announcement (PA-19-270)

SBIR Omnibus/Parent Clinical Trial Required Funding Opportunity Announcement (PA-19-273)

STTR Omnibus/Parent Clinical Trial Required Funding Opportunity Announcement (PA-19-271)

Deadlines: September 5, 2019; January 6, 2020; April 6, 2020

Announcement Number	Issuing Organization	Other Participating Organizations	Release Date	Opening Date (SF424 Only)	Receipt Date(s)	Expiration Date	Activity Code(s)	Title
RFA-HG-20-016	NHGRI	NCATS	03/19/2020	30 days prior to the application due date	June 24, 2020; February 1, 2021; October 1, 2021; June 24,2022 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	06/25/2022	R43/R44	Novel Synthetic Nucleic Acid Technology Development (R43/R44)( Clinical Trial not allowed)
RFA-CA-20-033	NCI		03/06/2020	July 3, 2020	August 3, 2020	08/04/2020	R44	SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)
PAR-20-111	NINDS	NCCIH, NIDCR, NIAAA, NICHD, NIDA, NIA, NEI, OBSSR, NIMH	03/03/2020	30 days prior to the application due date	August 11, 2020, February 9, 2021,August 10, 2021,February 9, 2022,August 9, 2022, February 9, 2023 by 5:00 PM local time of applicant organization.	05/08/2023	U44	Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
PAR-20-109	NCATS	NINDS, NIA, NIGMS, NIAID	02/06/2020	30 days prior to the application due date	Standard dates apply The first standard due date for this FOA is April 5, 2020	01/06/2022	R41/R42	Non-Viral Technologies for in vivo Delivery of Genome Editors (R41/R42 Clinical Trial Not Allowed)
PAR-20-098	NCATS	NIA, NIGMS, NIAID, NINDS	02/06/2020	30 days prior to the application due date	Standard dates apply The first standard due date for this FOA is April 5, 2020	01/06/2022	R43/R44	Non-Viral Technologies for in vivo Delivery of Genome Editors (R43/R44 Clinical Trial Not Allowed)
PA-20-025	NIMH	NIEHS, NIGMS, NCATS, NIDCR, NIDA, NEI, NHGRI	01/07/2020	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2023	R41/R42	Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed)
PA-20-047	NIMH	NIEHS, NIGMS, NCATS, NIDCR, NIDA, NEI, NHGRI	01/07/2020	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2023	R43/R44	Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed)
RFA-DK-19-028	NIDDK		12/10/2019	March 9, 2020 and October 3, 2020	April 9, 2020 and November 3, 2020 April 9, 2020 and November 3, 2020 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	11/04/2020	R43/R44	Support for Small Business Innovation Research (SBIR) to Development and Testing of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/R44 Clinical Trial Not Allowed)
RFA-DK-19-027	NIDDK		12/03/2019	March 9, 2020 and October 3, 2020	?April 9, 2020 and November 3, 2020	11/04/2020	R43/R44	Support for Small Business Innovation Research (SBIR) to Develop New Technologies for Development and Integration of Novel Components for Open and Closed Loop Hormone Replacement Platforms for T1D Therapy (R43/R44 Clinical Trial Not Allowed)
RFA-NS-20-009	NINDS	NICHD, NIBIB, NIMH, NIDDK, NIAAA, NCCIH, ORIP, NIA, NIAMS, NHLBI, NIGMS, NCI, NIMHD, NCATS, NEI, NINR, NIDCR, NLM	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R41/R42	HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
RFA-NS-20-008	NINDS	NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R41/R42	HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required)
RFA-NS-20-010	NINDS	NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R43/R44	HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)
RFA-NS-20-011	NINDS	NIAAA, NIA, NIAMS, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NLM, NIMH, NINR, NCATS, ORIP, NHLBI, NIDCR, NEI	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R43/R44	HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)
PAS-19-316	NIA	NINDS	07/18/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity are due on these dates. The first standard application due date for this FOA is September 5, 2019.	09/07/2022	R43/R44	Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)
PAS-19-317	NIA	NINDS	07/18/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity are due on these dates. The first standard application due date for this FOA is September 5, 2019.	09/07/2022	R41/R42	Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)
PA-19-272	NIH	NIAMS, NCIPC, NIAID, NIA, NIAAA, NLM, NCCIH, PS, ORIP, NIDCD, NCEH, GH, CK, NEI, NINDS, NIDCR, NHGRI, IP, NCBDD, CCDPH, NCATS, NHLBI, NIEHS, NIMH, NIBIB, NINR, NIOSH, NIMHD, NICHD, NIDA, NIGMS, NCI, FDA, NIDDK	05/07/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/07/2020	R43/R44	PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed
PA-19-273	NIH	NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NICHD, NIDA, NIDCD, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINR, NCEH, NCIPC, NIOSH	05/07/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/07/2020	R43/R44	PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required
PA-19-271	NIH	NHLBI, NCI, NCCIH, NIAAA, NIMH, NIEHS, NIMHD, NIGMS, NIDA, NIA, NINR, NIDCD, NEI, NICHD, NHGRI	05/07/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/07/2020	R41/R42	PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required
PA-19-270	NIH	NIAMS, NINR, NIAAA, NIDCD, NIDA, NCI, NIMH, NCCIH, NIDCR, ORIP, NHLBI, NINDS, NIGMS, NIEHS, NEI, NIAID, NIBIB, NIA, NIMHD, NIDDK, NCATS, NICHD, NHGRI, NLM	05/07/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/07/2020	R41/R42	PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed
PAR-19-266	ORIP		05/02/2019	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization.	04/06/2021	R41/R42	Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)
PAR-19-265	ORIP		05/02/2019	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization. by 5:00 PM local time of applicant organization. All types of applications allowed for this funding opportunity announcement are due on these dates.	04/06/2021	R43/R44	Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)
RFA-NS-19-017	NINDS	NINR, NCI, NIDA, NIDDK, NIAAA, NCATS, ORWH, NIMH, NIAMS, NICHD, NIBIB, NCCIH, NEI, NIDCR	12/10/2018	30 days prior to receipt date	January 9, 2019, March 22, 2019, May 2 0, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, February 21, 2021 , by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	02/23/2021	U44	HEAL Initiative: Translational Devices to Treat Pain (U44 Clinical Trial Optional)
RFA-DA-19-020	NIDA	NCATS	12/10/2018	30 days prior to the application due date	January 8, 2019, April 9, 2019, September 8, 2019, April 9, 2020, September 8, 2020, April 9, 2021, September 8, 2021, by 5:00 PM local time of applicant organization. No late applications will be accepted. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/09/2021	R41/R42	HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R41/R42 - Clinical Trial Optional)
RFA-DA-19-019	NIDA	NCATS	12/10/2018	30 days prior to application due date	January 8, 2019, April 9, 2019, September 8, 2019, April 9, 2020, September 8, 2020, April 9, 2021, September 8, 2021, by 5:00 PM local time of applicant organization. No late applications will be accepted. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/09/2021	R43/R44	HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R43/R44 - Clinical Trial Optional)
PA-19-076	NIDCR		11/26/2018	Not Applicable	Standard dates apply	01/06/2022	R43/R44	Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44 Clinical Trial Not Allowed)
PA-19-075	NIDCR		11/26/2018	Not Applicable	Standard dates apply	01/06/2022	R41/R42	Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42 Clinical Trial Not Allowed)
PAR-19-061	NHGRI		11/08/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/06/2021	R43/R44	Investigator Initiated Research in Computational Genomics and Data Science (R43/R44 Clinical Trial Not Allowed)
PA-19-043	NHGRI		10/31/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/06/2021	R43/R44	Novel Approaches for Relating Genetic Variation to Function and Disease (R43/R44 Clinical Trial Not Allowed)
PA-19-033	NIDCR	NCATS, NCI, NHLBI, NIMH, NLM	10/24/2018	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R41/R42	Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R41/R42 Clinical Trial Not Allowed)
PA-19-034	NIDCR	NCATS, NCI, NHLBI, NIMH, NLM	10/24/2018	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R43/R44	Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R43/R44 Clinical Trial Not Allowed)
PA-19-022	NIDCR		10/09/2018	Not Applicable	Standard dates apply	09/06/2021	R43/R44	Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44 Clinical Trial Not Allowed)
PA-19-021	NIDCR		10/09/2018	Not Applicable	Standard dates apply	09/06/2021	R41/R42	Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42 Clinical Trial Not Allowed)
PA-18-927	NIMH		09/19/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R41/R42	Innovative Technologies for HIV Behavioral and Social Science Research (R41/R42 Clinical Trial Optional)
PA-18-928	NIMH		09/19/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R43/R44	Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)
PA-18-870	NIMH	NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NINDS	07/24/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/07/2021	R41/R42	BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42 - Clinical Trials Not Allowed)
PA-18-871	NIMH	NEI, NICHD, NIAAA, NIDA, NCCIH, NIBIB, NINDS, NIDCD	07/24/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/07/2021	R43/R44	BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR) (R43/R44 - Clinical Trial Not Allowed)
PA-18-819	NIMH		06/06/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional)
PA-18-816	NIGMS		06/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R41/R42	Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42 - Clinical Trial Not Allowed)
PA-18-815	NIGMS		06/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44 - Clinical Trial Not Allowed)
PAR-18-801	NCI		05/24/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R43/R44 - Clinical Trial Optional)
PAR-18-802	NCI		05/24/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R41/R42	Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42 - Clinical Trial Optional)
RFA-HL-19-018	NHLBI	NCATS	05/16/2018	30 days prior to the application due date	July 27, 2018; July 9, 2019; July 9, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	07/10/2020	R44	NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)
RFA-HL-19-017	NHLBI		05/16/2018	30 days prior to the application due date	July 27, 2018; July 9, 2019; July 9, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	07/10/2020	R44	NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional)
PA-18-786	NIAAA		05/15/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)
PA-18-785	NIAAA		05/15/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R41/R42	Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)
PAR-18-779	NHGRI		05/09/2018	30 days prior to the application due date	October 2, 2018; October 2, 2019; October 2, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/08/2021	R43/R44	Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed)
RFA-HG-18-003	NHGRI		04/18/2018	30 days prior to the application due date	June 27, 2018; June 27, 2019; June 26, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/11/2020	R43/R44	Novel Nucleic Acid Sequencing Technology Development (R43/R44 Clinical Trial Not Allowed)
RFA-HL-19-016	NHLBI	NIBIB	03/15/2018	30 days prior to the application due date	June 11, 2018, September 10, 2018, June 10, 2019, September 10, 2019, and June 10, 2020, by 5:00 PM local time of applicant organization.	06/11/2020	R43	Technologies for Healthy Independent Living for Heart, Lung, Blood and Sleep Disorders (R43 - Clinical Trial Not Allowed)
PA-18-709	NIMH		03/15/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2021	R41/R42	Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42)-Clinical Trial Not Allowed
PA-18-708	NIMH		03/15/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	09/06/2021	R43/R44	Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)
PA-18-705	NINDS	NCI, NEI, NIA, NIAAA, NIDA, NIDCR, NINR	03/06/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)
PAR-18-665	NINDS		02/15/2018	30 days prior to the application due date	April 16th then Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R44	NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)
PAR-18-632	NIAID		02/06/2018	30 days prior to the application due date	May 14, 2018; September 13, 2018; January 14, 2019; May 13, 2019; September 13, 2019; January 13, 2020; May 13, 2020; September 14, 2020; January 13, 2021, by 5:00 PM local time of applicant organization.	01/14/2021	U44	NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)
PAR-18-628	NINDS		02/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	U44	NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)
PA-18-631	NIBIB		02/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	R44	NIBIB Exploratory Clinical Trials for Small Business (R44 Clinical Trial Required)
PAR-18-617	NINDS		02/01/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R42	NINDS Exploratory Clinical Trials for Small Business (R42) - Clinical Trial Required
PAR-18-618	NINDS		02/01/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R44	NINDS Exploratory Clinical Trials for Small Business (R44) - Clinical Trial Required
PA-18-609	ORIP	NIGMS	01/31/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R41/R42	Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R41/R42 Clinical Trial Not Allowed)
PA-18-610	ORIP	NIGMS	01/31/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R43/R44 Clinical Trial Not Allowed)
PAR-18-578	NIAAA		01/12/2018	30 days prior to the application due date	March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.	12/05/2020	U44	Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (U44 - Clinical Trial Optional)
PAR-18-580	NIAAA		01/12/2018	30 days before the due date	March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.	12/05/2020	UT2	Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (UT2 -Clinical Trial Optional)
PA-18-579	NIMH		01/12/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	R41/R42	Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)
PA-18-566	NIMH		01/12/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	R43/R44	Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44 Clinical Trial Optional)
PA-18-567	NIMH		01/09/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R44	Competing Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44 Clinical Trial Optional)
PAR-18-563	NINDS		01/09/2018	Not applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	U44	NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44 - Clinical Trials Optional)
PAR-18-549	NINDS		12/22/2017	30 days prior to the application due date	March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.	09/08/2020	U44	Analytical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)
PAR-18-548	NINDS		12/22/2017	30 days prior to the application due date	March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.	09/08/2020	U44	Clinical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)
RFA-NS-18-022	NINDS	NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NIMH	12/21/2017	30 days prior to the receipt date	February 23, 2018, June 21, 2018, October 22, 2018, February 21, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, by 5:00 PM local time of applicant organization.	10/22/2020	U44	BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)
PAR-18-512	NIA		12/20/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Testing Lifespan/Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R43/R44 Clinical Trial Not Allowed)
PAR-18-514	NIA		12/20/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R41/R42	Testing Lifespan-Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R41/R42 Clinical Trial Not Allowed)
PAR-18-543	NINDS		12/20/2017	Not Applicable	February 20, 2018, July 18, 2018, February 13, 2019, July 18, 2019, February 13, 2020, and July 20, 2020 , by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/08/2020	U44	CREATE Bio Development Track: Preclinical and Early-Phase Clinical Development for Biologics (U44 SBIR- Clinical Trial Optional)
PA-18-525	NIAID		12/19/2017	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R43/R44	Radiological/Nuclear Medical Countermeasure Product Development Program (SBIR) (R43/R44 Clinical Trial Not Allowed)
PAS-18-120	NCCIH		11/28/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2020	R43/R44	Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R43/R44 Clinical Trial Optional)
PAS-18-121	NCCIH		11/28/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2020	R41/R42	Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R41/R42 Clinical Trial Optional)
PAR-18-185	NIA		11/28/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2020	R41/R42	Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R41/R42 Clinical Trial Optional)
PAR-18-186	NIA		11/28/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2020	R43/R44	Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R43/R44 Clinical Trial Optional)
RFA-NS-18-012	NINDS		11/08/2017	30 days prior to the receipt date	February 21, 2018; June 21, 2018; October 22, 2018; February 21, 2019; June 21, 2019; October 21, 2019; February 21, 2020; June 22, 2020; and October 21, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	10/22/2020	U44	Translational Neural Devices (U44 - Clinical Trial Required)
PAR-18-303	NCI		10/03/2017	Not applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	01/08/2021	R43/R44	Innovative Molecular Analysis Technology Development for Cancer Research and Clinical Care (R43/R44 Clinical Trial Not Allowed)
PAR-17-480	NINDS		09/11/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	R44	NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44)
PAR-17-457	NINDS		08/14/2017	Not Applicable	February 13, 2018; July 18, 2018; February 13, 2019; July 18, 2019; February 13, 2020; and July 20, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/08/2020	U44	NINDS CREATE Bio Optimization Track for Biologics (U44)

Announcement
Number

Issuing
Organization

Other
Participating
Organizations

Release
Date

Opening Date
(SF424 Only)

Receipt
Date(s)

Expiration
Date

Activity
Code(s)

Title

RFA-HG-20-016

NHGRI

NCATS

03/19/2020

30 days prior to the application due date

June 24, 2020; February 1, 2021; October 1, 2021; June 24,2022 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

06/25/2022

R43/R44

Novel Synthetic Nucleic Acid Technology Development (R43/R44)( Clinical Trial not allowed)

RFA-CA-20-033

NCI

03/06/2020

July 3, 2020

August 3, 2020

08/04/2020

R44

SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)

PAR-20-111

NINDS

NCCIH, NIDCR, NIAAA, NICHD, NIDA, NIA, NEI, OBSSR, NIMH

03/03/2020

30 days prior to the application due date

August 11, 2020, February 9, 2021,August 10, 2021,February 9, 2022,August 9, 2022, February 9, 2023 by 5:00 PM local time of applicant organization.

05/08/2023

U44

Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)

PAR-20-109

NCATS

NINDS, NIA, NIGMS, NIAID

02/06/2020

30 days prior to the application due date

Standard dates apply The first standard due date for this FOA is April 5, 2020

01/06/2022

R41/R42

Non-Viral Technologies for in vivo Delivery of Genome Editors (R41/R42 Clinical Trial Not Allowed)

PAR-20-098

NCATS

NIA, NIGMS, NIAID, NINDS

02/06/2020

30 days prior to the application due date

Standard dates apply The first standard due date for this FOA is April 5, 2020

01/06/2022

R43/R44

Non-Viral Technologies for in vivo Delivery of Genome Editors (R43/R44 Clinical Trial Not Allowed)

PA-20-025

NIMH

NIEHS, NIGMS, NCATS, NIDCR, NIDA, NEI, NHGRI

01/07/2020

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2023

R41/R42

Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed)

PA-20-047

NIMH

NIEHS, NIGMS, NCATS, NIDCR, NIDA, NEI, NHGRI

01/07/2020

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2023

R43/R44

Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed)

RFA-DK-19-028

NIDDK

12/10/2019

March 9, 2020 and October 3, 2020

April 9, 2020 and November 3, 2020 April 9, 2020 and November 3, 2020 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

11/04/2020

R43/R44

Support for Small Business Innovation Research (SBIR) to Development and Testing of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/R44 Clinical Trial Not Allowed)

RFA-DK-19-027

NIDDK

12/03/2019

March 9, 2020 and October 3, 2020

?April 9, 2020 and November 3, 2020

11/04/2020

R43/R44

Support for Small Business Innovation Research (SBIR) to Develop New Technologies for Development and Integration of Novel Components for Open and Closed Loop Hormone Replacement Platforms for T1D Therapy (R43/R44 Clinical Trial Not Allowed)

RFA-NS-20-009

NINDS

NICHD, NIBIB, NIMH, NIDDK, NIAAA, NCCIH, ORIP, NIA, NIAMS, NHLBI, NIGMS, NCI, NIMHD, NCATS, NEI, NINR, NIDCR, NLM

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R41/R42

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)

RFA-NS-20-008

NINDS

NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R41/R42

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required)

RFA-NS-20-010

NINDS

NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R43/R44

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)

RFA-NS-20-011

NINDS

NIAAA, NIA, NIAMS, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NLM, NIMH, NINR, NCATS, ORIP, NHLBI, NIDCR, NEI

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R43/R44

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)

PAS-19-316

NIA

NINDS

07/18/2019

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity are due on these dates. The first standard application due date for this FOA is September 5, 2019.

09/07/2022

R43/R44

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)

PAS-19-317

NIA

NINDS

07/18/2019

Not Applicable

09/07/2022

R41/R42

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)

PA-19-272

NIH

NIAMS, NCIPC, NIAID, NIA, NIAAA, NLM, NCCIH, PS, ORIP, NIDCD, NCEH, GH, CK, NEI, NINDS, NIDCR, NHGRI, IP, NCBDD, CCDPH, NCATS, NHLBI, NIEHS, NIMH, NIBIB, NINR, NIOSH, NIMHD, NICHD, NIDA, NIGMS, NCI, FDA, NIDDK

05/07/2019

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

04/07/2020

R43/R44

PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed

PA-19-273

NIH

NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NICHD, NIDA, NIDCD, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINR, NCEH, NCIPC, NIOSH

05/07/2019

Not Applicable

04/07/2020

R43/R44

PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required

PA-19-271

NIH

NHLBI, NCI, NCCIH, NIAAA, NIMH, NIEHS, NIMHD, NIGMS, NIDA, NIA, NINR, NIDCD, NEI, NICHD, NHGRI

05/07/2019

Not Applicable

04/07/2020

R41/R42

PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required

PA-19-270

NIH

NIAMS, NINR, NIAAA, NIDCD, NIDA, NCI, NIMH, NCCIH, NIDCR, ORIP, NHLBI, NINDS, NIGMS, NIEHS, NEI, NIAID, NIBIB, NIA, NIMHD, NIDDK, NCATS, NICHD, NHGRI, NLM

05/07/2019

Not Applicable

04/07/2020

R41/R42

PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed

PAR-19-266

ORIP

05/02/2019

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization.

04/06/2021

R41/R42

Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)

PAR-19-265

ORIP

05/02/2019

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization. by 5:00 PM local time of applicant organization. All types of applications allowed for this funding opportunity announcement are due on these dates.

04/06/2021

R43/R44

Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)

RFA-NS-19-017

NINDS

NINR, NCI, NIDA, NIDDK, NIAAA, NCATS, ORWH, NIMH, NIAMS, NICHD, NIBIB, NCCIH, NEI, NIDCR

12/10/2018

30 days prior to receipt date

January 9, 2019, March 22, 2019, May 2 0, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, February 21, 2021 , by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

02/23/2021

U44

HEAL Initiative: Translational Devices to Treat Pain (U44 Clinical Trial Optional)

RFA-DA-19-020

NIDA

NCATS

12/10/2018

30 days prior to the application due date

January 8, 2019, April 9, 2019, September 8, 2019, April 9, 2020, September 8, 2020, April 9, 2021, September 8, 2021, by 5:00 PM local time of applicant organization. No late applications will be accepted. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/09/2021

R41/R42

HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R41/R42 - Clinical Trial Optional)

RFA-DA-19-019

NIDA

NCATS

12/10/2018

30 days prior to application due date

09/09/2021

R43/R44

HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R43/R44 - Clinical Trial Optional)

PA-19-076

NIDCR

11/26/2018

Not Applicable

Standard dates apply

01/06/2022

R43/R44

Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44 Clinical Trial Not Allowed)

PA-19-075

NIDCR

11/26/2018

Not Applicable

Standard dates apply

01/06/2022

R41/R42

Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42 Clinical Trial Not Allowed)

PAR-19-061

NHGRI

11/08/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/06/2021

R43/R44

Investigator Initiated Research in Computational Genomics and Data Science (R43/R44 Clinical Trial Not Allowed)

PA-19-043

NHGRI

10/31/2018

30 days prior to the application due date

09/06/2021

R43/R44

Novel Approaches for Relating Genetic Variation to Function and Disease (R43/R44 Clinical Trial Not Allowed)

PA-19-033

NIDCR

NCATS, NCI, NHLBI, NIMH, NLM

10/24/2018

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R41/R42

Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R41/R42 Clinical Trial Not Allowed)

PA-19-034

NIDCR

NCATS, NCI, NHLBI, NIMH, NLM

10/24/2018

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R43/R44

Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R43/R44 Clinical Trial Not Allowed)

PA-19-022

NIDCR

10/09/2018

Not Applicable

Standard dates apply

09/06/2021

R43/R44

Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44 Clinical Trial Not Allowed)

PA-19-021

NIDCR

10/09/2018

Not Applicable

Standard dates apply

09/06/2021

R41/R42

Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42 Clinical Trial Not Allowed)

PA-18-927

NIMH

09/19/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R41/R42

Innovative Technologies for HIV Behavioral and Social Science Research (R41/R42 Clinical Trial Optional)

PA-18-928

NIMH

09/19/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R43/R44

Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)

PA-18-870

NIMH

NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NINDS

07/24/2018

Not Applicable

05/07/2021

R41/R42

BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42 - Clinical Trials Not Allowed)

PA-18-871

NIMH

NEI, NICHD, NIAAA, NIDA, NCCIH, NIBIB, NINDS, NIDCD

07/24/2018

Not Applicable

05/07/2021

R43/R44

BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR) (R43/R44 - Clinical Trial Not Allowed)

PA-18-819

NIMH

06/06/2018

30 days prior to the application due date

01/06/2021

R43/R44

Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional)

PA-18-816

NIGMS

06/05/2018

Not Applicable

04/06/2021

R41/R42

Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42 - Clinical Trial Not Allowed)

PA-18-815

NIGMS

06/05/2018

Not Applicable

04/06/2021

R43/R44

Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44 - Clinical Trial Not Allowed)

PAR-18-801

NCI

05/24/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/06/2021

R43/R44

Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R43/R44 - Clinical Trial Optional)

PAR-18-802

NCI

05/24/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/06/2021

R41/R42

Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42 - Clinical Trial Optional)

RFA-HL-19-018

NHLBI

NCATS

05/16/2018

30 days prior to the application due date

July 27, 2018; July 9, 2019; July 9, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

07/10/2020

R44

NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

RFA-HL-19-017

NHLBI

05/16/2018

30 days prior to the application due date

07/10/2020

R44

NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional)

PA-18-786

NIAAA

05/15/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

04/06/2021

R43/R44

Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)

PA-18-785

NIAAA

05/15/2018

Not Applicable

04/06/2021

R41/R42

Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)

PAR-18-779

NHGRI

05/09/2018

30 days prior to the application due date

October 2, 2018; October 2, 2019; October 2, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/08/2021

R43/R44

Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed)

RFA-HG-18-003

NHGRI

04/18/2018

30 days prior to the application due date

June 27, 2018; June 27, 2019; June 26, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/11/2020

R43/R44

Novel Nucleic Acid Sequencing Technology Development (R43/R44 Clinical Trial Not Allowed)

RFA-HL-19-016

NHLBI

NIBIB

03/15/2018

30 days prior to the application due date

June 11, 2018, September 10, 2018, June 10, 2019, September 10, 2019, and June 10, 2020, by 5:00 PM local time of applicant organization.

06/11/2020

R43

Technologies for Healthy Independent Living for Heart, Lung, Blood and Sleep Disorders (R43 - Clinical Trial Not Allowed)

PA-18-709

NIMH

03/15/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2021

R41/R42

Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42)-Clinical Trial Not Allowed

PA-18-708

NIMH

03/15/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

09/06/2021

R43/R44

Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)

PA-18-705

NINDS

NCI, NEI, NIA, NIAAA, NIDA, NIDCR, NINR

03/06/2018

Not Applicable

04/06/2021

R43/R44

SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)

PAR-18-665

NINDS

02/15/2018

30 days prior to the application due date

April 16th then Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R44

NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)

PAR-18-632

NIAID

02/06/2018

30 days prior to the application due date

May 14, 2018; September 13, 2018; January 14, 2019; May 13, 2019; September 13, 2019; January 13, 2020; May 13, 2020; September 14, 2020; January 13, 2021, by 5:00 PM local time of applicant organization.

01/14/2021

U44

NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)

PAR-18-628

NINDS

02/05/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

U44

NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)

PA-18-631

NIBIB

02/05/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

R44

NIBIB Exploratory Clinical Trials for Small Business (R44 Clinical Trial Required)

PAR-18-617

NINDS

02/01/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R42

NINDS Exploratory Clinical Trials for Small Business (R42) - Clinical Trial Required

PAR-18-618

NINDS

02/01/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R44

NINDS Exploratory Clinical Trials for Small Business (R44) - Clinical Trial Required

PA-18-609

ORIP

NIGMS

01/31/2018

Not Applicable

01/06/2021

R41/R42

Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R41/R42 Clinical Trial Not Allowed)

PA-18-610

ORIP

NIGMS

01/31/2018

Not Applicable

01/06/2021

R43/R44

Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R43/R44 Clinical Trial Not Allowed)

PAR-18-578

NIAAA

01/12/2018

30 days prior to the application due date

March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.

12/05/2020

U44

Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (U44 - Clinical Trial Optional)

PAR-18-580

NIAAA

01/12/2018

30 days before the due date

March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.

12/05/2020

UT2

Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (UT2 -Clinical Trial Optional)

PA-18-579

NIMH

01/12/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

R41/R42

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)

PA-18-566

NIMH

01/12/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

R43/R44

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44 Clinical Trial Optional)

PA-18-567

NIMH

01/09/2018

Not Applicable

01/06/2021

R44

Competing Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44 Clinical Trial Optional)

PAR-18-563

NINDS

01/09/2018

Not applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

U44

NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44 - Clinical Trials Optional)

PAR-18-549

NINDS

12/22/2017

30 days prior to the application due date

March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.

09/08/2020

U44

Analytical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)

PAR-18-548

NINDS

12/22/2017

30 days prior to the application due date

March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.

09/08/2020

U44

Clinical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)

RFA-NS-18-022

NINDS

NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NIMH

12/21/2017

30 days prior to the receipt date

February 23, 2018, June 21, 2018, October 22, 2018, February 21, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, by 5:00 PM local time of applicant organization.

10/22/2020

U44

BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)

PAR-18-512

NIA

12/20/2017

Not Applicable

01/06/2021

R43/R44

Testing Lifespan/Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R43/R44 Clinical Trial Not Allowed)

PAR-18-514

NIA

12/20/2017

Not Applicable

01/06/2021

R41/R42

Testing Lifespan-Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R41/R42 Clinical Trial Not Allowed)

PAR-18-543

NINDS

12/20/2017

Not Applicable

February 20, 2018, July 18, 2018, February 13, 2019, July 18, 2019, February 13, 2020, and July 20, 2020 , by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/08/2020

U44

CREATE Bio Development Track: Preclinical and Early-Phase Clinical Development for Biologics (U44 SBIR- Clinical Trial Optional)

PA-18-525

NIAID

12/19/2017

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R43/R44

Radiological/Nuclear Medical Countermeasure Product Development Program (SBIR) (R43/R44 Clinical Trial Not Allowed)

PAS-18-120

NCCIH

11/28/2017

Not Applicable

04/06/2020

R43/R44

Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R43/R44 Clinical Trial Optional)

PAS-18-121

NCCIH

11/28/2017

Not Applicable

04/06/2020

R41/R42

Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R41/R42 Clinical Trial Optional)

PAR-18-185

NIA

11/28/2017

30 days prior to the application due date

04/06/2020

R41/R42

Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R41/R42 Clinical Trial Optional)

PAR-18-186

NIA

11/28/2017

30 days prior to the application due date

04/06/2020

R43/R44

Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R43/R44 Clinical Trial Optional)

RFA-NS-18-012

NINDS

11/08/2017

30 days prior to the receipt date

February 21, 2018; June 21, 2018; October 22, 2018; February 21, 2019; June 21, 2019; October 21, 2019; February 21, 2020; June 22, 2020; and October 21, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

10/22/2020

U44

Translational Neural Devices (U44 - Clinical Trial Required)

PAR-18-303

NCI

10/03/2017

Not applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

01/08/2021

R43/R44

Innovative Molecular Analysis Technology Development for Cancer Research and Clinical Care (R43/R44 Clinical Trial Not Allowed)

PAR-17-480

NINDS

09/11/2017

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

R44

NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44)

PAR-17-457

NINDS

08/14/2017

Not Applicable

February 13, 2018; July 18, 2018; February 13, 2019; July 18, 2019; February 13, 2020; and July 20, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/08/2020

U44

NINDS CREATE Bio Optimization Track for Biologics (U44)

Targeted SBIR/STTR Funding Announcements

SBIR and STTR Omnibus Solicitations (Parent Announcements)

SBIR and STTR Funding Opportunities (80 Records - Sorted by Release Date)