Special Announcements for Small Business Research Opportunities

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The SBIR/STTR Program

Targeted SBIR/STTR Funding Announcements

Receipt dates for the following Program Announcements (PAs) and Request for Applications (RFAs) may vary. See the NIH Guide for Grants and Contracts for all NIH RFA and PA announcements.

SBIR and STTR Omnibus Solicitations (Parent Announcements)

SBIR Omnibus/Parent Clinical Trial Not Allowed Funding Opportunity Announcement (PA-18-574)

STTR Omnibus/Parent Clinical Trial Not Allowed Funding Opportunity Announcement (PA-18-575)

SBIR Omnibus/Parent Clinical Trial Required Funding Opportunity Announcement (PA-18-573)

STTR Omnibus/Parent Clinical Trial Required Funding Opportunity Announcement (PA-18-576)

Deadlines: April 5, 2018; September 5, 2018; January 7, 2019; April 5, 2019

Announcement Number	Issuing Organization	Other Participating Organizations	Release Date	Opening Date (SF424 Only)	Receipt Date(s)	Expiration Date	Activity Code(s)	Title
PA-19-022	NIDCR		10/09/2018	Not Applicable	Standard dates apply	09/06/2021	R43/R44	Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44 Clinical Trial Not Allowed)
PA-19-021	NIDCR		10/09/2018	Not Applicable	Standard dates apply	09/06/2021	R41/R42	Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42 Clinical Trial Not Allowed)
RFA-DA-19-014	NIDA		09/19/2018	November 14, 2018	December 14, 2018, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	12/15/2018	R43/R44	Loyalty and Reward-Based Technologies to Increase Adherence to Substance Use Disorder Pharmacotherapies (R43/R44 - Clinical Trial Optional)
RFA-DA-19-015	NIDA		09/19/2018	November 14, 2018	December 14, 2018, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	12/15/2018	R41/R42	Loyalty and Reward-Based Technologies to Increase Adherence to Substance Use Disorder Pharmacotherapies (R41/R42 - Clinical Trial Optional)
PA-18-927	NIMH		09/19/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R41/R42	Innovative Technologies for HIV Behavioral and Social Science Research (R41/R42 Clinical Trial Optional)
PA-18-928	NIMH		09/19/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R43/R44	Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)
RFA-MD-18-010	NIMHD	NIMH	08/01/2018	March 1, 2019	April 1, 2019, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/02/2019	R41/R42	Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
RFA-HL-18-033	NHLBI	NIA, NIAID, NIAMS, NIDCD, NIDDK, NIBIB, NIMH, NINDS, NCATS, NIDCR, NEI	08/01/2018	September 19, 2018	October 19, 2018, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	10/20/2018	UT2	Regenerative Medicine Innovation Projects (RMIP) (UT2 - Clinical Trial Not Allowed)
RFA-HL-18-035	NHLBI	NIA, NIAID, NIAMS, NIDCD, NIDDK, NIBIB, NIMH, NINDS, NCATS, NIDCR, NEI	08/01/2018	September 19, 2018	October 19, 2018, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on this date. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	10/20/2018	U44	Regenerative Medicine Innovation Projects (RMIP) (U44 - Clinical Trial Not Allowed)
PA-18-870	NIMH	NIDA, NIAAA, NEI, NIDCD, NCCIH, NINDS, NIBIB, NICHD	07/24/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/07/2021	R41/R42	BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42 - Clinical Trials Not Allowed)
PA-18-871	NIMH	NEI, NICHD, NIAAA, NIDA, NCCIH, NIBIB, NINDS, NIDCD	07/24/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/07/2021	R43/R44	BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR) (R43/R44 - Clinical Trial Not Allowed)
PA-18-819	NIMH		06/06/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional)
PA-18-816	NIGMS		06/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R41/R42	Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42 - Clinical Trial Not Allowed)
PA-18-815	NIGMS		06/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44 - Clinical Trial Not Allowed)
PAR-18-801	NCI		05/24/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R43/R44 - Clinical Trial Optional)
PAR-18-802	NCI		05/24/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R41/R42	Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42 - Clinical Trial Optional)
RFA-HL-19-018	NHLBI	NCATS	05/16/2018	30 days prior to the application due date	July 27, 2018; July 9, 2019; July 9, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	07/10/2020	R44	NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)
RFA-HL-19-017	NHLBI		05/16/2018	30 days prior to the application due date	July 27, 2018; July 9, 2019; July 9, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	07/10/2020	R44	NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional)
PA-18-786	NIAAA		05/15/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)
PA-18-785	NIAAA		05/15/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R41/R42	Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)
PAR-18-779	NHGRI		05/09/2018	30 days prior to the application due date	October 2, 2018; October 2, 2019; October 2, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/08/2021	R43/R44	Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed)
RFA-HG-18-003	NHGRI		04/18/2018	30 days prior to the application due date	June 27, 2018; June 27, 2019; June 26, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/11/2020	R43/R44	Novel Nucleic Acid Sequencing Technology Development (R43/R44 Clinical Trial Not Allowed)
RFA-HL-19-016	NHLBI	NIBIB	03/15/2018	30 days prior to the application due date	June 11, 2018, September 10, 2018, June 10, 2019, September 10, 2019, and June 10, 2020, by 5:00 PM local time of applicant organization.	09/11/2020	R43	Technologies for Healthy Independent Living for Heart, Lung, Blood and Sleep Disorders (R43 - Clinical Trial Not Allowed)
PA-18-709	NIMH		03/15/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2021	R41/R42	Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42)-Clinical Trial Not Allowed
PA-18-708	NIMH		03/15/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	09/06/2021	R43/R44	Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)
PA-18-705	NINDS	NCI, NIAAA, NEI, NIDCR, NIDA, NINR	03/06/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)
PA-18-682	NCCIH		02/26/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2019	R41/R42	Methods Development in Natural Products Chemistry (R41/R42 Clinical Trial Not Allowed)
PAR-18-665	NINDS		02/15/2018	30 days prior to the application due date	April 16th then Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R44	NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)
PAR-18-632	NIAID		02/06/2018	30 days prior to the application due date	May 14, 2018; September 13, 2018; January 14, 2019; May 13, 2019; September 13, 2019; January 13, 2020; May 13, 2020; September 14, 2020; January 13, 2021, by 5:00 PM local time of applicant organization.	01/14/2021	U44	NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)
PAR-18-628	NINDS		02/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	U44	NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)
PA-18-631	NIBIB		02/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	R44	NIBIB Exploratory Clinical Trials for Small Business (R44 Clinical Trial Required)
PAR-18-617	NINDS		02/01/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R42	NINDS Exploratory Clinical Trials for Small Business (R42) - Clinical Trial Required
PAR-18-618	NINDS		02/01/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R44	NINDS Exploratory Clinical Trials for Small Business (R44) - Clinical Trial Required
PA-18-609	ORIP	NIGMS	01/31/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R41/R42	Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R41/R42 Clinical Trial Not Allowed)
PA-18-610	ORIP	NIGMS	01/31/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R43/R44 Clinical Trial Not Allowed)
PA-18-607	NCCIH		01/30/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2019	R43/R44	Methods Development in Natural Products Chemistry (R43/R44 Clinical Trial Not Allowed)
PAR-18-588	NIA		01/26/2018	30 days prior to the application due date	April 10, 2018, January 8, 2019, and January 8, 2020, by 5:00 PM local time of applicant organization.	01/09/2020	R43/R44	Assistive Technology for Persons with Alzheimer's Disease and Related Dementias and Their Caregivers (R43/R44 - Clinical Trial Optional)
PAR-18-587	NIA		01/26/2018	30 days prior to the application due date	April 10, 2018, January 8, 2019, and January 8, 2020, by 5:00 PM local time of applicant organization.	01/09/2020	R41/R42	Assistive Technology for Persons with Alzheimer's Disease and Related Dementias and Their Caregivers (R41/R42 - Clinical Trials Optional)
PA-18-573	NIH	NCCIH, NEI, NHGRI, NHLBI, NIA, NIAAA, NICHD, NIDA, NIDCD, NIGMS, NIMH, NIMHD, NINR, NCI, NIDCR	01/16/2018	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization.	04/06/2019	R43/R44	PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
PA-18-576	NIH	NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIDA, NIDCD, NIDCR, NIGMS, NIMH, NIMHD, NINR, NICHD	01/16/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2019	R41/R42	PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
PA-18-575	NIH	NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, ORIP	01/16/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	04/06/2019	R41/R42	PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
PA-18-574	NIH	NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, ORIP, CBER, CFSAN, CGH, FDA, NCBDDD, NCEH, NCEZID, NCHHSTP, NCHSTP, NCIPC, NIOSH, OPHPR	01/16/2018	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization.	04/06/2019	R43/R44	PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
PAR-18-578	NIAAA		01/12/2018	30 days prior to the application due date	March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.	12/05/2020	U44	Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (U44 - Clinical Trial Optional)
PAR-18-580	NIAAA		01/12/2018	30 days before the due date	March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.	12/05/2020	UT2	Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (UT2 -Clinical Trial Optional)
PA-18-579	NIMH		01/12/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	R41/R42	Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)
PA-18-566	NIMH		01/12/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2021	R43/R44	Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44 Clinical Trial Optional)
PA-18-567	NIMH		01/09/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R44	Competing Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44 Clinical Trial Optional)
PAR-18-563	NINDS		01/09/2018	Not applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	U44	NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44 - Clinical Trials Optional)
PAR-18-549	NINDS		12/22/2017	30 days prior to the application due date	March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.	09/08/2020	U44	Analytical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)
PAR-18-548	NINDS		12/22/2017	30 days prior to the application due date	March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.	09/08/2020	U44	Clinical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)
RFA-NS-18-022	NINDS	NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NIMH	12/21/2017	30 days prior to the receipt date	February 23, 2018, June 21, 2018, October 22, 2018, February 21, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, by 5:00 PM local time of applicant organization.	10/22/2020	U44	BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)
PAR-18-541	NINDS	NCCIH, NEI, NIA, NIAAA, NICHD, NIDA, NIDCR, NIMH	12/21/2017	30 days prior to the application due date	February 7, 2018, August 9, 2018, February 9, 2019, August 9, 2019, February 11, 2020, by 5:00 PM local time of applicant organization.	05/08/2020	U44	Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44) - Clinical Trial Optional
PAR-18-512	NIA		12/20/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R43/R44	Testing Lifespan/Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R43/R44 Clinical Trial Not Allowed)
PAR-18-514	NIA		12/20/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2021	R41/R42	Testing Lifespan-Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R41/R42 Clinical Trial Not Allowed)
PAR-18-543	NINDS		12/20/2017	Not Applicable	February 20, 2018, July 18, 2018, February 13, 2019, July 18, 2019, February 13, 2020, and July 20, 2020 , by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/08/2020	U44	CREATE Bio Development Track: Preclinical and Early-Phase Clinical Development for Biologics (U44 SBIR- Clinical Trial Optional)
PA-18-525	NIAID		12/19/2017	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	01/06/2021	R43/R44	Radiological/Nuclear Medical Countermeasure Product Development Program (SBIR) (R43/R44 Clinical Trial Not Allowed)
PAR-18-108	NIDDK		11/28/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2019	R44	NIDDK Exploratory Clinical Trials for Small Business (R44 Clinical Trial Required)
PAS-18-120	NCCIH		11/28/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R43/R44	Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R43/R44 Clinical Trial Optional)
PAS-18-121	NCCIH		11/28/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R41/R42	Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R41/R42 Clinical Trial Optional)
PAR-18-183	NIA		11/28/2017	30 days before application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2019	R43/R44	T1 Translational Research on Aging: Small Business Innovation Awards (R43/R44 Clinical Trial Optional)
PAR-18-184	NIA		11/28/2017	30 days before application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2019	R43/R44	T2 Translational Research on Aging: Small Business Innovation Awards (R43/R44 Clinical Trial Optional)
PAR-18-185	NIA		11/28/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2020	R41/R42	Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R41/R42 Clinical Trial Optional)
PAR-18-186	NIA		11/28/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2020	R43/R44	Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R43/R44 Clinical Trial Optional)
PAR-18-269	NIMH		11/28/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2019	R43/R44	Products to Support Applied Research Towards Zero Suicide Healthcare Systems (R43/R44 Clinical Trial Optional)
PAS-18-187	NIA		11/28/2017	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	09/06/2019	R43/R44	Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)
PAS-18-188	NIA		11/28/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2019	R41/R42	Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)
RFA-NS-18-012	NINDS		11/08/2017	30 days prior to the receipt date	February 21, 2018; June 21, 2018; October 22, 2018; February 21, 2019; June 21, 2019; October 21, 2019; February 21, 2020; June 22, 2020; and October 21, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	10/22/2020	U44	Translational Neural Devices (U44 - Clinical Trial Required)
PAR-18-326	NIA		10/25/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R41/R42	Technology to Detect, Monitor and Assess Daily Functions in Individuals with Cognitive Decline, Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD) (R41/R42 Clinical Trial Not Allowed)
PAR-18-329	NIA		10/25/2017	Not Applicable	(Standard dates apply), by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R43/R44	Technology to Detect, Monitor and Assess Daily Functions in Individuals with Cognitive Decline, Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD) (R43/R44 Clinical Trial Not Allowed)
PAR-18-403	NIGMS		10/04/2017	Not Applicable	January 5, 2018; September 5, 2018; September 5, 2019, by 5:00 PM local time of applicant organization.	09/06/2019	R41/R42	Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (STTR) (R41/R42 - Clinical Trial Not Allowed)
PAR-18-402	NIGMS		10/04/2017	Not Applicable	January 5, 2018; September 5, 2018; September 5, 2019, by 5:00 PM local time of applicant organization.	09/06/2019	R43/R44	Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) (R43/R44 - Clinical Trial Not Allowed)
PAR-18-303	NCI		10/03/2017	Not applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	01/08/2021	R43/R44	Innovative Molecular Analysis Technology Development for Cancer Research and Clinical Care (R43/R44 Clinical Trial Not Allowed)
PAR-17-480	NINDS		09/11/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2020	R44	NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44)
PAR-17-457	NINDS		08/14/2017	Not Applicable	February 13, 2018; July 18, 2018; February 13, 2019; July 18, 2019; February 13, 2020; and July 20, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/08/2020	U44	NINDS CREATE Bio Optimization Track for Biologics (U44)
PAR-17-200	NICHD	NIDCD	03/29/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R41	Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R41)
PAR-17-199	NICHD	NIDCD	03/29/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R43	Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R43)
PA-17-147	NIMH	NCATS, NCCIH, NCI, NEI, NHGRI, NIAMS, NIDA, NIDCR, NIDDK, NIEHS, NIGMS	02/01/2017	Not applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R43/R44	Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44)
PA-17-148	NIMH	NCATS, NCCIH, NCI, NHGRI, NIAMS, NIDCR, NIDDK, NIEHS	02/01/2017	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R41/R42	Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42)
PA-17-130	NIDDK		01/24/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2020	R43/R44	Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R43/R44)
PA-17-131	NIDDK		01/24/2017	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2020	R41/R42	Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R41/R42)
PAR-17-067	NIA		12/02/2016	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2019	R43/R44	Tools for Clinical Care and Management of Alzheimers Disease (AD) and its Comorbidities (R43/R44)
PAR-17-066	NIA		12/02/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2019	R41/R42	Tools for Clinical Care and Management of Alzheimers Disease (AD) and Its Comorbidities (R41/R42)
PAR-17-036	NCATS	NIAID	10/27/2016	Not Applicable.	Standard dates apply by 5:00 PM local time of applicant organization.	09/06/2019	R41/R42	Platform Delivery Technologies for Nucleic Acid Therapeutics (R41/R42)
PAR-17-035	NCATS	NIAID, NIBIB	10/27/2016	Not Applicable.	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2019	R43/R44	Platform Delivery Technologies for Nucleic Acid Therapeutics (R43/R44)
PA-16-451	NIDDK		09/28/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R41/R42	Kidney Precision Medicine Project - Technology Development and Validation (R41/R42)
PA-16-452	NIDDK		09/28/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	01/06/2020	R43/R44	Kidney Precision Medicine Project - Technology Development and Validation (R43/R44)
PA-16-208	NIAID		04/19/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	04/06/2019	R41/R42	The Use of mRNA for an HIV Envelope Vaccine (R41/R42)
PA-16-207	NIAID		04/19/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	04/06/2019	R43/R44	The Use of mRNA for an HIV Envelope Vaccine (R43/R44)
PA-16-186	NIGMS	NCATS, NCI, NHGRI, NIA, NIAID, NIBIB, NIDA, NIDCR, NINDS, ORIP, ORWH	04/15/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	04/06/2019	R43/R44	Tools for Cell Line Identification (R43/R44)
PA-16-184	NIAID		04/12/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2019	R43/R44	Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R43/R44)
PA-16-182	NIAID		04/12/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2019	R41/R42	Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R41/R42)
PA-16-180	ORIP		04/11/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	04/06/2019	R43/R44	Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R43/R44)
PA-16-181	ORIP		04/11/2016	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	04/06/2019	R41/R42	Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R41/R42)
PA-16-158	NIGMS	NEI, NIDCR	03/30/2016	Not Applicable	Standard Due Dates	04/06/2019	R41/R42	New Technologies for the Glycosciences (R41/R42)
PA-16-157	NIGMS	NEI, NIDCR	03/30/2016	Not Applicable	Standard Due Dates	04/06/2019	R43/R44	New Technologies for the Glycosciences (R43/R44)

Announcement
Number

Issuing
Organization

Other
Participating
Organizations

Release
Date

Opening Date
(SF424 Only)

Receipt
Date(s)

Expiration
Date

Activity
Code(s)

Title

PA-19-022

NIDCR

10/09/2018

Not Applicable

Standard dates apply

09/06/2021

R43/R44

Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44 Clinical Trial Not Allowed)

PA-19-021

NIDCR

10/09/2018

Not Applicable

Standard dates apply

09/06/2021

R41/R42

Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42 Clinical Trial Not Allowed)

RFA-DA-19-014

NIDA

09/19/2018

November 14, 2018

December 14, 2018, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

12/15/2018

R43/R44

Loyalty and Reward-Based Technologies to Increase Adherence to Substance Use Disorder Pharmacotherapies (R43/R44 - Clinical Trial Optional)

RFA-DA-19-015

NIDA

09/19/2018

November 14, 2018

12/15/2018

R41/R42

Loyalty and Reward-Based Technologies to Increase Adherence to Substance Use Disorder Pharmacotherapies (R41/R42 - Clinical Trial Optional)

PA-18-927

NIMH

09/19/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R41/R42

Innovative Technologies for HIV Behavioral and Social Science Research (R41/R42 Clinical Trial Optional)

PA-18-928

NIMH

09/19/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R43/R44

Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)

RFA-MD-18-010

NIMHD

NIMH

08/01/2018

March 1, 2019

April 1, 2019, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

04/02/2019

R41/R42

Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)

RFA-HL-18-033

NHLBI

NIA, NIAID, NIAMS, NIDCD, NIDDK, NIBIB, NIMH, NINDS, NCATS, NIDCR, NEI

08/01/2018

September 19, 2018

October 19, 2018, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

10/20/2018

UT2

Regenerative Medicine Innovation Projects (RMIP) (UT2 - Clinical Trial Not Allowed)

RFA-HL-18-035

NHLBI

NIA, NIAID, NIAMS, NIDCD, NIDDK, NIBIB, NIMH, NINDS, NCATS, NIDCR, NEI

08/01/2018

September 19, 2018

October 19, 2018, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on this date. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

10/20/2018

U44

Regenerative Medicine Innovation Projects (RMIP) (U44 - Clinical Trial Not Allowed)

PA-18-870

NIMH

NIDA, NIAAA, NEI, NIDCD, NCCIH, NINDS, NIBIB, NICHD

07/24/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

05/07/2021

R41/R42

BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42 - Clinical Trials Not Allowed)

PA-18-871

NIMH

NEI, NICHD, NIAAA, NIDA, NCCIH, NIBIB, NINDS, NIDCD

07/24/2018

Not Applicable

05/07/2021

R43/R44

BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR) (R43/R44 - Clinical Trial Not Allowed)

PA-18-819

NIMH

06/06/2018

30 days prior to the application due date

01/06/2021

R43/R44

Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional)

PA-18-816

NIGMS

06/05/2018

Not Applicable

04/06/2021

R41/R42

Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42 - Clinical Trial Not Allowed)

PA-18-815

NIGMS

06/05/2018

Not Applicable

04/06/2021

R43/R44

Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44 - Clinical Trial Not Allowed)

PAR-18-801

NCI

05/24/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/06/2021

R43/R44

Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R43/R44 - Clinical Trial Optional)

PAR-18-802

NCI

05/24/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/06/2021

R41/R42

Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42 - Clinical Trial Optional)

RFA-HL-19-018

NHLBI

NCATS

05/16/2018

30 days prior to the application due date

July 27, 2018; July 9, 2019; July 9, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

07/10/2020

R44

NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

RFA-HL-19-017

NHLBI

05/16/2018

30 days prior to the application due date

07/10/2020

R44

NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional)

PA-18-786

NIAAA

05/15/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

04/06/2021

R43/R44

Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)

PA-18-785

NIAAA

05/15/2018

Not Applicable

04/06/2021

R41/R42

Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)

PAR-18-779

NHGRI

05/09/2018

30 days prior to the application due date

October 2, 2018; October 2, 2019; October 2, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/08/2021

R43/R44

Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed)

RFA-HG-18-003

NHGRI

04/18/2018

30 days prior to the application due date

June 27, 2018; June 27, 2019; June 26, 2020, by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/11/2020

R43/R44

Novel Nucleic Acid Sequencing Technology Development (R43/R44 Clinical Trial Not Allowed)

RFA-HL-19-016

NHLBI

NIBIB

03/15/2018

30 days prior to the application due date

June 11, 2018, September 10, 2018, June 10, 2019, September 10, 2019, and June 10, 2020, by 5:00 PM local time of applicant organization.

09/11/2020

R43

Technologies for Healthy Independent Living for Heart, Lung, Blood and Sleep Disorders (R43 - Clinical Trial Not Allowed)

PA-18-709

NIMH

03/15/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2021

R41/R42

Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42)-Clinical Trial Not Allowed

PA-18-708

NIMH

03/15/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

09/06/2021

R43/R44

Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)

PA-18-705

NINDS

NCI, NIAAA, NEI, NIDCR, NIDA, NINR

03/06/2018

Not Applicable

04/06/2021

R43/R44

SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)

PA-18-682

NCCIH

02/26/2018

Not Applicable

04/06/2019

R41/R42

Methods Development in Natural Products Chemistry (R41/R42 Clinical Trial Not Allowed)

PAR-18-665

NINDS

02/15/2018

30 days prior to the application due date

April 16th then Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R44

NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)

PAR-18-632

NIAID

02/06/2018

30 days prior to the application due date

May 14, 2018; September 13, 2018; January 14, 2019; May 13, 2019; September 13, 2019; January 13, 2020; May 13, 2020; September 14, 2020; January 13, 2021, by 5:00 PM local time of applicant organization.

01/14/2021

U44

NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)

PAR-18-628

NINDS

02/05/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

U44

NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)

PA-18-631

NIBIB

02/05/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

R44

NIBIB Exploratory Clinical Trials for Small Business (R44 Clinical Trial Required)

PAR-18-617

NINDS

02/01/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R42

NINDS Exploratory Clinical Trials for Small Business (R42) - Clinical Trial Required

PAR-18-618

NINDS

02/01/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R44

NINDS Exploratory Clinical Trials for Small Business (R44) - Clinical Trial Required

PA-18-609

ORIP

NIGMS

01/31/2018

Not Applicable

01/06/2021

R41/R42

Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R41/R42 Clinical Trial Not Allowed)

PA-18-610

ORIP

NIGMS

01/31/2018

Not Applicable

01/06/2021

R43/R44

Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R43/R44 Clinical Trial Not Allowed)

PA-18-607

NCCIH

01/30/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2019

R43/R44

Methods Development in Natural Products Chemistry (R43/R44 Clinical Trial Not Allowed)

PAR-18-588

NIA

01/26/2018

30 days prior to the application due date

April 10, 2018, January 8, 2019, and January 8, 2020, by 5:00 PM local time of applicant organization.

01/09/2020

R43/R44

Assistive Technology for Persons with Alzheimer's Disease and Related Dementias and Their Caregivers (R43/R44 - Clinical Trial Optional)

PAR-18-587

NIA

01/26/2018

30 days prior to the application due date

April 10, 2018, January 8, 2019, and January 8, 2020, by 5:00 PM local time of applicant organization.

01/09/2020

R41/R42

Assistive Technology for Persons with Alzheimer's Disease and Related Dementias and Their Caregivers (R41/R42 - Clinical Trials Optional)

PA-18-573

NIH

NCCIH, NEI, NHGRI, NHLBI, NIA, NIAAA, NICHD, NIDA, NIDCD, NIGMS, NIMH, NIMHD, NINR, NCI, NIDCR

01/16/2018

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization.

04/06/2019

R43/R44

PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)

PA-18-576

NIH

NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIDA, NIDCD, NIDCR, NIGMS, NIMH, NIMHD, NINR, NICHD

01/16/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2019

R41/R42

PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)

PA-18-575

NIH

NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, ORIP

01/16/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

04/06/2019

R41/R42

PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)

PA-18-574

NIH

NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, ORIP, CBER, CFSAN, CGH, FDA, NCBDDD, NCEH, NCEZID, NCHHSTP, NCHSTP, NCIPC, NIOSH, OPHPR

01/16/2018

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization.

04/06/2019

R43/R44

PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)

PAR-18-578

NIAAA

01/12/2018

30 days prior to the application due date

March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.

12/05/2020

U44

Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (U44 - Clinical Trial Optional)

PAR-18-580

NIAAA

01/12/2018

30 days before the due date

March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.

12/05/2020

UT2

Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (UT2 -Clinical Trial Optional)

PA-18-579

NIMH

01/12/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

R41/R42

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)

PA-18-566

NIMH

01/12/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2021

R43/R44

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44 Clinical Trial Optional)

PA-18-567

NIMH

01/09/2018

Not Applicable

01/06/2021

R44

Competing Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44 Clinical Trial Optional)

PAR-18-563

NINDS

01/09/2018

Not applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

U44

NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44 - Clinical Trials Optional)

PAR-18-549

NINDS

12/22/2017

30 days prior to the application due date

March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.

09/08/2020

U44

Analytical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)

PAR-18-548

NINDS

12/22/2017

30 days prior to the application due date

March 14, 2018; July 18, 2018; February 14, 2019; July 18, 2019; February 14, 2020; and July 20, 2020, by 5:00 PM local time of applicant organization.

09/08/2020

U44

Clinical Validation of a Candidate Biomarker for Neurological Disease (U44 - Clinical Trial Optional)

RFA-NS-18-022

NINDS

NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NIMH

12/21/2017

30 days prior to the receipt date

February 23, 2018, June 21, 2018, October 22, 2018, February 21, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, by 5:00 PM local time of applicant organization.

10/22/2020

U44

BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)

PAR-18-541

NINDS

NCCIH, NEI, NIA, NIAAA, NICHD, NIDA, NIDCR, NIMH

12/21/2017

30 days prior to the application due date

February 7, 2018, August 9, 2018, February 9, 2019, August 9, 2019, February 11, 2020, by 5:00 PM local time of applicant organization.

05/08/2020

U44

Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44) - Clinical Trial Optional

PAR-18-512

NIA

12/20/2017

Not Applicable

01/06/2021

R43/R44

Testing Lifespan/Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R43/R44 Clinical Trial Not Allowed)

PAR-18-514

NIA

12/20/2017

Not Applicable

01/06/2021

R41/R42

Testing Lifespan-Healthspan-Extension Interventions in the Models of Alzheimers Disease (AD/ADRD) (R41/R42 Clinical Trial Not Allowed)

PAR-18-543

NINDS

12/20/2017

Not Applicable

February 20, 2018, July 18, 2018, February 13, 2019, July 18, 2019, February 13, 2020, and July 20, 2020 , by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/08/2020

U44

CREATE Bio Development Track: Preclinical and Early-Phase Clinical Development for Biologics (U44 SBIR- Clinical Trial Optional)

PA-18-525

NIAID

12/19/2017

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

01/06/2021

R43/R44

Radiological/Nuclear Medical Countermeasure Product Development Program (SBIR) (R43/R44 Clinical Trial Not Allowed)

PAR-18-108

NIDDK

11/28/2017

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2019

R44

NIDDK Exploratory Clinical Trials for Small Business (R44 Clinical Trial Required)

PAS-18-120

NCCIH

11/28/2017

Not Applicable

01/06/2020

R43/R44

Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R43/R44 Clinical Trial Optional)

PAS-18-121

NCCIH

11/28/2017

Not Applicable

01/06/2020

R41/R42

Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R41/R42 Clinical Trial Optional)

PAR-18-183

NIA

11/28/2017

30 days before application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2019

R43/R44

T1 Translational Research on Aging: Small Business Innovation Awards (R43/R44 Clinical Trial Optional)

PAR-18-184

NIA

11/28/2017

30 days before application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2019

R43/R44

T2 Translational Research on Aging: Small Business Innovation Awards (R43/R44 Clinical Trial Optional)

PAR-18-185

NIA

11/28/2017

30 days prior to the application due date

04/06/2020

R41/R42

Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R41/R42 Clinical Trial Optional)

PAR-18-186

NIA

11/28/2017

30 days prior to the application due date

04/06/2020

R43/R44

Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R43/R44 Clinical Trial Optional)

PAR-18-269

NIMH

11/28/2017

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2019

R43/R44

Products to Support Applied Research Towards Zero Suicide Healthcare Systems (R43/R44 Clinical Trial Optional)

PAS-18-187

NIA

11/28/2017

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

09/06/2019

R43/R44

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)

PAS-18-188

NIA

11/28/2017

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2019

R41/R42

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)

RFA-NS-18-012

NINDS

11/08/2017

30 days prior to the receipt date

February 21, 2018; June 21, 2018; October 22, 2018; February 21, 2019; June 21, 2019; October 21, 2019; February 21, 2020; June 22, 2020; and October 21, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

10/22/2020

U44

Translational Neural Devices (U44 - Clinical Trial Required)

PAR-18-326

NIA

10/25/2017

Not Applicable

01/06/2020

R41/R42

Technology to Detect, Monitor and Assess Daily Functions in Individuals with Cognitive Decline, Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD) (R41/R42 Clinical Trial Not Allowed)

PAR-18-329

NIA

10/25/2017

Not Applicable

(Standard dates apply), by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/06/2020

R43/R44

PAR-18-403

NIGMS

10/04/2017

Not Applicable

January 5, 2018; September 5, 2018; September 5, 2019, by 5:00 PM local time of applicant organization.

09/06/2019

R41/R42

Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (STTR) (R41/R42 - Clinical Trial Not Allowed)

PAR-18-402

NIGMS

10/04/2017

Not Applicable

January 5, 2018; September 5, 2018; September 5, 2019, by 5:00 PM local time of applicant organization.

09/06/2019

R43/R44

Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) (R43/R44 - Clinical Trial Not Allowed)

PAR-18-303

NCI

10/03/2017

Not applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

01/08/2021

R43/R44

Innovative Molecular Analysis Technology Development for Cancer Research and Clinical Care (R43/R44 Clinical Trial Not Allowed)

PAR-17-480

NINDS

09/11/2017

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2020

R44

NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44)

PAR-17-457

NINDS

08/14/2017

Not Applicable

February 13, 2018; July 18, 2018; February 13, 2019; July 18, 2019; February 13, 2020; and July 20, 2020 , by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/08/2020

U44

NINDS CREATE Bio Optimization Track for Biologics (U44)

PAR-17-200

NICHD

NIDCD

03/29/2017

30 days prior to the application due date

01/06/2020

R41

Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R41)

PAR-17-199

NICHD

NIDCD

03/29/2017

30 days prior to the application due date

01/06/2020

R43

Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R43)

PA-17-147

NIMH

NCATS, NCCIH, NCI, NEI, NHGRI, NIAMS, NIDA, NIDCR, NIDDK, NIEHS, NIGMS

02/01/2017

Not applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

01/06/2020

R43/R44

Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44)

PA-17-148

NIMH

NCATS, NCCIH, NCI, NHGRI, NIAMS, NIDCR, NIDDK, NIEHS

02/01/2017

30 days prior to the application due date

01/06/2020

R41/R42

Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42)

PA-17-130

NIDDK

01/24/2017

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2020

R43/R44

Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R43/R44)

PA-17-131

NIDDK

01/24/2017

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2020

R41/R42

Lead Optimization and Preclinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (R41/R42)

PAR-17-067

NIA

12/02/2016

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2019

R43/R44

Tools for Clinical Care and Management of Alzheimers Disease (AD) and its Comorbidities (R43/R44)

PAR-17-066

NIA

12/02/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2019

R41/R42

Tools for Clinical Care and Management of Alzheimers Disease (AD) and Its Comorbidities (R41/R42)

PAR-17-036

NCATS

NIAID

10/27/2016

Not Applicable.

Standard dates apply by 5:00 PM local time of applicant organization.

09/06/2019

R41/R42

Platform Delivery Technologies for Nucleic Acid Therapeutics (R41/R42)

PAR-17-035

NCATS

NIAID, NIBIB

10/27/2016

Not Applicable.

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2019

R43/R44

Platform Delivery Technologies for Nucleic Acid Therapeutics (R43/R44)

PA-16-451

NIDDK

09/28/2016

Not Applicable

01/06/2020

R41/R42

Kidney Precision Medicine Project - Technology Development and Validation (R41/R42)

PA-16-452

NIDDK

09/28/2016

Not Applicable

01/06/2020

R43/R44

Kidney Precision Medicine Project - Technology Development and Validation (R43/R44)

PA-16-208

NIAID

04/19/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

04/06/2019

R41/R42

The Use of mRNA for an HIV Envelope Vaccine (R41/R42)

PA-16-207

NIAID

04/19/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

04/06/2019

R43/R44

The Use of mRNA for an HIV Envelope Vaccine (R43/R44)

PA-16-186

NIGMS

NCATS, NCI, NHGRI, NIA, NIAID, NIBIB, NIDA, NIDCR, NINDS, ORIP, ORWH

04/15/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

04/06/2019

R43/R44

Tools for Cell Line Identification (R43/R44)

PA-16-184

NIAID

04/12/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2019

R43/R44

Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R43/R44)

PA-16-182

NIAID

04/12/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2019

R41/R42

Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R41/R42)

PA-16-180

ORIP

04/11/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

04/06/2019

R43/R44

Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R43/R44)

PA-16-181

ORIP

04/11/2016

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

04/06/2019

R41/R42

Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R41/R42)

PA-16-158

NIGMS

NEI, NIDCR

03/30/2016

Not Applicable

Standard Due Dates

04/06/2019

R41/R42

New Technologies for the Glycosciences (R41/R42)

PA-16-157

NIGMS

NEI, NIDCR

03/30/2016

Not Applicable

Standard Due Dates

04/06/2019

R43/R44

New Technologies for the Glycosciences (R43/R44)

Targeted SBIR/STTR Funding Announcements

SBIR and STTR Omnibus Solicitations (Parent Announcements)

SBIR and STTR Funding Opportunities (95 Records - Sorted by Release Date)