Special Announcements for Small Business Research Opportunities

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The SBIR/STTR Program

Targeted SBIR/STTR Funding Announcements

Receipt dates for the following Program Announcements (PAs) and Request for Applications (RFAs) may vary. See the NIH Guide for Grants and Contracts for all NIH RFA and PA announcements.

SBIR and STTR Omnibus Solicitations (Parent Announcements)

SBIR Omnibus/Parent Clinical Trial Not Allowed Funding Opportunity Announcement (PA-20-260)

STTR Omnibus/Parent Clinical Trial Not Allowed Funding Opportunity Announcement (PA-20-265)

SBIR Omnibus/Parent Clinical Trial Required Funding Opportunity Announcement (PA-20-262)

STTR Omnibus/Parent Clinical Trial Required Funding Opportunity Announcement (PA-20-261)

Deadlines: September 8, 2020; January 5, 2021; April 5, 2021

Announcement Number	Issuing Organization	Other Participating Organizations	Release Date	Opening Date (SF424 Only)	Receipt Date(s)	Expiration Date	Activity Code(s)	Title
PAR-21-082	NIAID		01/14/2021	30 days prior to the application due date	May 14, 2021; September 13, 2021; January 14, 2022; May 13, 2022; September 13, 2022; January 13, 2023; May 13, 2023; September 14, 2023; January 13, 2024	01/14/2024	U44	NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)
RFA-TR-21-010	NCATS		01/13/2021	March 13, 2021	April 13, 2021, September 13, 2021, January 12, 2022	01/13/2022	U44	Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases (U44 Clinical Trial Required)
RFA-DA-21-015	NIDA		12/23/2020	January 26, 2021	February 26, 2021	02/27/2021	R41/R42	Novel Approaches to Decrease Stigma of Substance Use Disorders in order to Facilitate Prevention, Treatment, and Support During Recovery (R41/R42 - Clinical Trials Optional)
RFA-DA-21-016	NIDA		12/23/2020	January 26, 2021	February 26, 2021	02/27/2021	R43/R44	Novel Approaches to Decrease Stigma of Substance Use Disorders in order to Facilitate Prevention, Treatment, and Support During Recovery (R43/R44 - Clinical Trials Optional)
RFA-DA-21-031	NIDA		12/22/2020	December 26, 2020	January 26, 2021	02/27/2021	R41/R42	Digital Technologies to Address the Social Determinants of Health in Context of Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)
RFA-DA-21-032	NIDA		12/22/2020	December 26, 2020	January 26, 2021	01/27/2021	R43/R44	Digital Technologies to Address the Social Determinants of Health in Context of Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)
RFA-ES-21-002	NIEHS		12/10/2020	February 28, 2021	March 29, 2021	03/30/2021	R43	Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R43 Clinical Trial Not Allowed)
RFA-ES-21-003	NIEHS		12/10/2020	February 28, 2021	March 29, 2021	03/30/2021	R41	Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R41 Clinical Trial Not Allowed)
RFA-CA-21-001	NCI	NHGRI	11/25/2020	30 days prior to the application due date	March 10, 2021 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	03/11/2021	R42	Small Business Transition Grant For Early Career Scientists (R42 Clinical Trial Not Allowed)
PAR-21-059	NINDS		11/19/2020	30 days prior to the application due date.	February 22, 2021, June 22, 2021, February 22, 2022, June 22, 2022, February 22, 2023, and June 22, 2023	09/08/2023	U44	Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)
PAR-21-057	NINDS		11/19/2020	30 days prior to the application due date.	February 22, 2021, June 22, 2021, February 22, 2022 June 22, 2022, February 22, 2023, June 22, 2023	09/08/2023	U44	Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)
RFA-MH-21-112	NIMH		11/13/2020	30 days prior to the application due date	?February 18, 2021; October 15, 2021, June 15, 2022	06/16/2022	R43/R44	Service-Ready Tools for Identification, Prevention, and Treatment of Individuals at Risk for Suicide (R43/R44 Clinical Trial Optional)
PAR-21-030	NIAMS		10/08/2020	December 5, 2020	Standard datesapply The first standard due date for this FOA is January 5, 2021.	09/06/2022	R43/R44	Late-Stage Translation of Biomedical and Behavioral Research Results in Arthritis and Musculoskeletal and Skin Diseases from Academic/Non-profit Lab to Marketplace (SBIR [R43/R44] Clinical Trial Not Allowed)
PA-20-260	NIH	NHGRI, NCCIH, ORIP, NIAAA, NEI, NIDA, NIDCR, NIDCD, NIMHD, NIMH, NCBDD, CCDPH, GH, CK, NCEH, NCI, NIEHS, NHLBI, NINDS, NLM, NIAMS, NICHD, FDA, NIGMS, NINR, NIAID, CTPER, PS, IP, NIDDK, NIBIB, NCATS, NIA, NCIPC, NIOSH	07/14/2020	Not Applicable	Standard dates apply All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
PA-20-261	NIH	NHGRI, NCCIH, NIAAA, NCI, NEI, NIDA, NIDCD, NIMHD, NICHD, NIMH, NHLBI, NIGMS, NIEHS, NINR, NIA	07/14/2020	Not Applicable	Standard dates apply All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date	04/06/2021	R41/R42	PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
PA-20-262	NIH	NCCIH, NHGRI, NIAAA, NEI, NIDA, NCEH, NIOSH, NCIPC, PS, CTPER, NIDCD, NIMHD, NICHD, NIMH, NCI, NHLBI, GH, FDA, NIGMS, NIEHS, NINR, NCBDD, IP, CCDPH, CK, NIDDK, NIA	07/14/2020	Not Applicable	Standard dates apply All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	PHS 2020-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
PA-20-265	NIH	NHGRI, ORIP, NIAAA, NCCIH, NEI, NIAMS, NIDCR, NIMHD, NICHD, NIMH, NCI, NHLBI, NIDA, NIDCD, NLM, NIGMS, NIEHS, NINR, NIAID, NIDDK, NIBIB, NINDS, NCATS, NIA	07/14/2020	Not Applicable	Standard dates apply All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R41/R42	PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
PAR-20-239	NIGMS		06/25/2020	Not Applicable	September 4, 2020; September 3, 2021; September 2, 2022	09/03/2022	R41/R42	Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (STTR) (R41/R42 Clinical Trial Not Allowed)
PAR-20-244	NIGMS		06/25/2020	Not Applicable	September 4, 2020; September 3, 2021; September 2 , 2022	09/03/2022	R43/R44	Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) (R43/R44 Clinical Trial Not Allowed)
RFA-HG-20-016	NHGRI	NCATS	03/19/2020	30 days prior to the application due date	June 24, 2020; March 9, 2021; February 4, 2022 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	02/05/2022	R43/R44	Novel Synthetic Nucleic Acid Technology Development (R43/R44)( Clinical Trial not allowed)
PAR-20-111	NINDS	NCCIH, NIDCR, NIAAA, NICHD, NIDA, NIA, NEI, OBSSR, NIMH	03/03/2020	30 days prior to the application due date	August 11, 2020, February 9, 2021,August 10, 2021,February 9, 2022,August 9, 2022, February 9, 2023 by 5:00 PM local time of applicant organization.	05/08/2023	U44	Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
PAR-20-109	NCATS	NINDS, NIA, NIGMS, NIAID	02/06/2020	30 days prior to the application due date	Standard dates apply The first standard due date for this FOA is April 5, 2020	01/06/2022	R41/R42	Non-Viral Technologies for in vivo Delivery of Genome Editors (R41/R42 Clinical Trial Not Allowed)
PAR-20-098	NCATS	NIA, NIGMS, NIAID, NINDS	02/06/2020	30 days prior to the application due date	Standard dates apply The first standard due date for this FOA is April 5, 2020	01/06/2022	R43/R44	Non-Viral Technologies for in vivo Delivery of Genome Editors (R43/R44 Clinical Trial Not Allowed)
PA-20-025	NIMH	NIEHS, NIGMS, NCATS, NIDCR, NIDA, NEI, NHGRI	01/07/2020	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2023	R41/R42	Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed)
PA-20-047	NIMH	NCATS, NCI, NEI, NHGRI, NIDA, NIDCR, NIEHS, NIGMS	01/07/2020	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	01/06/2023	R43/R44	Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed)
RFA-NS-20-009	NINDS	NICHD, NIBIB, NIMH, NIDDK, NIAAA, NCCIH, ORIP, NIA, NIAMS, NHLBI, NIGMS, NCI, NIMHD, NCATS, NEI, NINR, NIDCR, NLM	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R41/R42	HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
RFA-NS-20-008	NINDS	NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R41/R42	HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required)
RFA-NS-20-010	NINDS	NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R43/R44	HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)
RFA-NS-20-011	NINDS	NIAAA, NIA, NIAMS, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NLM, NIMH, NINR, NCATS, ORIP, NHLBI, NIDCR, NEI	10/04/2019	30 days prior to the application due date	January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022	09/09/2022	R43/R44	HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)
PAS-19-316	NIA	NINDS	07/18/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity are due on these dates. The first standard application due date for this FOA is September 5, 2019.	09/07/2022	R43/R44	Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)
PAS-19-317	NIA	NINDS	07/18/2019	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity are due on these dates. The first standard application due date for this FOA is September 5, 2019.	09/07/2022	R41/R42	Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)
PAR-19-266	ORIP		05/02/2019	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization.	04/06/2021	R41/R42	Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)
PAR-19-265	ORIP		05/02/2019	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization. by 5:00 PM local time of applicant organization. All types of applications allowed for this funding opportunity announcement are due on these dates.	04/06/2021	R43/R44	Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)
RFA-DA-19-020	NIDA	NCATS	12/10/2018	30 days prior to the application due date	January 8, 2019, April 9, 2019, September 8, 2019, April 9, 2020, September 8, 2020, April 9, 2021, September 8, 2021, by 5:00 PM local time of applicant organization. No late applications will be accepted. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/09/2021	R41/R42	HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R41/R42 - Clinical Trial Optional)
RFA-DA-19-019	NIDA	NCATS	12/10/2018	30 days prior to application due date	January 8, 2019, April 9, 2019, September 8, 2019, April 9, 2020, September 8, 2020, April 9, 2021, September 8, 2021, by 5:00 PM local time of applicant organization. No late applications will be accepted. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/09/2021	R43/R44	HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R43/R44 - Clinical Trial Optional)
PA-19-076	NIDCR		11/26/2018	Not Applicable	Standard dates apply	01/06/2022	R43/R44	Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44 Clinical Trial Not Allowed)
PA-19-075	NIDCR		11/26/2018	Not Applicable	Standard dates apply	01/06/2022	R41/R42	Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42 Clinical Trial Not Allowed)
PAR-19-061	NHGRI		11/08/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/06/2021	R43/R44	Investigator Initiated Research in Computational Genomics and Data Science (R43/R44 Clinical Trial Not Allowed)
PA-19-043	NHGRI		10/31/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	09/06/2021	R43/R44	Novel Approaches for Relating Genetic Variation to Function and Disease (R43/R44 Clinical Trial Not Allowed)
PA-19-033	NIDCR	NCATS, NCI, NHLBI, NIMH, NLM	10/24/2018	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R41/R42	Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R41/R42 Clinical Trial Not Allowed)
PA-19-034	NIDCR	NCATS, NCI, NHLBI, NIMH, NLM	10/24/2018	Not Applicable	Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R43/R44	Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R43/R44 Clinical Trial Not Allowed)
PA-19-022	NIDCR		10/09/2018	Not Applicable	Standard dates apply	09/06/2021	R43/R44	Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44 Clinical Trial Not Allowed)
PA-19-021	NIDCR		10/09/2018	Not Applicable	Standard dates apply	09/06/2021	R41/R42	Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42 Clinical Trial Not Allowed)
PA-18-927	NIMH		09/19/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R41/R42	Innovative Technologies for HIV Behavioral and Social Science Research (R41/R42 Clinical Trial Optional)
PA-18-928	NIMH		09/19/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.	09/06/2021	R43/R44	Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)
PA-18-870	NIMH	NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NINDS	07/24/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/07/2021	R41/R42	BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42 - Clinical Trials Not Allowed)
PA-18-871	NIMH	NEI, NICHD, NIAAA, NIDA, NCCIH, NIBIB, NINDS, NIDCD	07/24/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/07/2021	R43/R44	BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR) (R43/R44 - Clinical Trial Not Allowed)
PA-18-819	NIMH		06/06/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional)
PA-18-816	NIGMS		06/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R41/R42	Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42 - Clinical Trial Not Allowed)
PA-18-815	NIGMS		06/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44 - Clinical Trial Not Allowed)
PA-18-786	NIAAA		05/15/2018	Not Applicable	Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)
PA-18-785	NIAAA		05/15/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R41/R42	Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)
PA-18-709	NIMH		03/15/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	09/06/2021	R41/R42	Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42)-Clinical Trial Not Allowed
PA-18-708	NIMH		03/15/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	09/06/2021	R43/R44	Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)
PA-18-705	NINDS	NCI, NEI, NIA, NIAAA, NIDA, NIDCR, NINR	03/06/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R43/R44	SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)
PAR-18-665	NINDS		02/15/2018	30 days prior to the application due date	April 16th then Standard dates apply , by 5:00 PM local time of applicant organization.	04/06/2021	R44	NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)
PAR-18-628	NINDS		02/05/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2021	U44	NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)
PAR-18-617	NINDS		02/01/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	04/06/2021	R42	NINDS Exploratory Clinical Trials for Small Business (R42) - Clinical Trial Required
PAR-18-618	NINDS		02/01/2018	30 days prior to the application due date	Standard dates apply , by 5:00 PM local time of applicant organization.	04/06/2021	R44	NINDS Exploratory Clinical Trials for Small Business (R44) - Clinical Trial Required
PAR-18-578	NIAAA		01/12/2018	30 days prior to the application due date	March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020; March 25, 2021, by 5:00 PM local time of applicant organization.	03/26/2021	U44	Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (U44 - Clinical Trial Optional)
PAR-18-580	NIAAA		01/12/2018	30 days before the due date	March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.	03/26/2021	UT2	Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (UT2 -Clinical Trial Optional)
PA-18-579	NIMH		01/12/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2021	R41/R42	Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)
PA-18-566	NIMH		01/12/2018	30 days prior to the application due date	Standard dates apply, by 5:00 PM local time of applicant organization.	04/06/2021	R43/R44	Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44 Clinical Trial Optional)
PA-18-567	NIMH		01/09/2018	Not Applicable	Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	04/06/2021	R44	Competing Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44 Clinical Trial Optional)
PAR-18-563	NINDS		01/09/2018	Not applicable	Standard dates apply , by 5:00 PM local time of applicant organization.	04/06/2021	U44	NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44 - Clinical Trials Optional)
RFA-NS-18-022	NINDS	NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NIMH	12/21/2017	30 days prior to the receipt date	February 23, 2018, June 21, 2018, October 22, 2018, February 21, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, by 5:00 PM local time of applicant organization.	02/23/2021	U44	BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)
PAR-18-543	NINDS		12/20/2017	Not Applicable	February 20, 2018, July 18, 2018, February 13, 2019, July 18, 2019, February 13, 2020, July 20, 2020), and February 12, 2021 by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/08/2021	U44	CREATE Bio Development Track: Preclinical and Early-Phase Clinical Development for Biologics (U44 SBIR- Clinical Trial Optional)
RFA-NS-18-012	NINDS		11/08/2017	30 days prior to the receipt date	February 21, 2018; June 21, 2018; October 22, 2018; February 21, 2019; June 21, 2019; October 21, 2019; February 21, 2020; June 22, 2020; and October 21, 2020 , February 22, 2021 by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	02/23/2021	U44	Translational Neural Devices (U44 - Clinical Trial Required)
PAR-17-457	NINDS		08/14/2017	Not Applicable	February 13, 2018; July 18, 2018; February 13, 2019; July 18, 2019; February 13, 2020; and July 20, 2020 , February 12, 2021 by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.	05/08/2021	U44	NINDS CREATE Bio Optimization Track for Biologics (U44)

Announcement
Number

Issuing
Organization

Other
Participating
Organizations

Release
Date

Opening Date
(SF424 Only)

Receipt
Date(s)

Expiration
Date

Activity
Code(s)

Title

PAR-21-082

NIAID

01/14/2021

30 days prior to the application due date

May 14, 2021; September 13, 2021; January 14, 2022; May 13, 2022; September 13, 2022; January 13, 2023; May 13, 2023; September 14, 2023; January 13, 2024

01/14/2024

U44

NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)

RFA-TR-21-010

NCATS

01/13/2021

March 13, 2021

April 13, 2021, September 13, 2021, January 12, 2022

01/13/2022

U44

Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases (U44 Clinical Trial Required)

RFA-DA-21-015

NIDA

12/23/2020

January 26, 2021

February 26, 2021

02/27/2021

R41/R42

Novel Approaches to Decrease Stigma of Substance Use Disorders in order to Facilitate Prevention, Treatment, and Support During Recovery (R41/R42 - Clinical Trials Optional)

RFA-DA-21-016

NIDA

12/23/2020

January 26, 2021

February 26, 2021

02/27/2021

R43/R44

Novel Approaches to Decrease Stigma of Substance Use Disorders in order to Facilitate Prevention, Treatment, and Support During Recovery (R43/R44 - Clinical Trials Optional)

RFA-DA-21-031

NIDA

12/22/2020

December 26, 2020

January 26, 2021

02/27/2021

R41/R42

Digital Technologies to Address the Social Determinants of Health in Context of Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)

RFA-DA-21-032

NIDA

12/22/2020

December 26, 2020

January 26, 2021

01/27/2021

R43/R44

Digital Technologies to Address the Social Determinants of Health in Context of Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)

RFA-ES-21-002

NIEHS

12/10/2020

February 28, 2021

March 29, 2021

03/30/2021

R43

Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R43 Clinical Trial Not Allowed)

RFA-ES-21-003

NIEHS

12/10/2020

February 28, 2021

March 29, 2021

03/30/2021

R41

Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R41 Clinical Trial Not Allowed)

RFA-CA-21-001

NCI

NHGRI

11/25/2020

30 days prior to the application due date

March 10, 2021 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

03/11/2021

R42

Small Business Transition Grant For Early Career Scientists (R42 Clinical Trial Not Allowed)

PAR-21-059

NINDS

11/19/2020

30 days prior to the application due date.

February 22, 2021, June 22, 2021, February 22, 2022, June 22, 2022, February 22, 2023, and June 22, 2023

09/08/2023

U44

Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)

PAR-21-057

NINDS

11/19/2020

30 days prior to the application due date.

February 22, 2021, June 22, 2021, February 22, 2022 June 22, 2022, February 22, 2023, June 22, 2023

09/08/2023

U44

Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)

RFA-MH-21-112

NIMH

11/13/2020

30 days prior to the application due date

?February 18, 2021; October 15, 2021, June 15, 2022

06/16/2022

R43/R44

Service-Ready Tools for Identification, Prevention, and Treatment of Individuals at Risk for Suicide (R43/R44 Clinical Trial Optional)

PAR-21-030

NIAMS

10/08/2020

December 5, 2020

Standard datesapply The first standard due date for this FOA is January 5, 2021.

09/06/2022

R43/R44

Late-Stage Translation of Biomedical and Behavioral Research Results in Arthritis and Musculoskeletal and Skin Diseases from Academic/Non-profit Lab to Marketplace (SBIR [R43/R44] Clinical Trial Not Allowed)

PA-20-260

NIH

NHGRI, NCCIH, ORIP, NIAAA, NEI, NIDA, NIDCR, NIDCD, NIMHD, NIMH, NCBDD, CCDPH, GH, CK, NCEH, NCI, NIEHS, NHLBI, NINDS, NLM, NIAMS, NICHD, FDA, NIGMS, NINR, NIAID, CTPER, PS, IP, NIDDK, NIBIB, NCATS, NIA, NCIPC, NIOSH

07/14/2020

Not Applicable

Standard dates apply All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

04/06/2021

R43/R44

PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)

PA-20-261

NIH

NHGRI, NCCIH, NIAAA, NCI, NEI, NIDA, NIDCD, NIMHD, NICHD, NIMH, NHLBI, NIGMS, NIEHS, NINR, NIA

07/14/2020

Not Applicable

04/06/2021

R41/R42

PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)

PA-20-262

NIH

NCCIH, NHGRI, NIAAA, NEI, NIDA, NCEH, NIOSH, NCIPC, PS, CTPER, NIDCD, NIMHD, NICHD, NIMH, NCI, NHLBI, GH, FDA, NIGMS, NIEHS, NINR, NCBDD, IP, CCDPH, CK, NIDDK, NIA

07/14/2020

Not Applicable

04/06/2021

R43/R44

PHS 2020-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)

PA-20-265

NIH

NHGRI, ORIP, NIAAA, NCCIH, NEI, NIAMS, NIDCR, NIMHD, NICHD, NIMH, NCI, NHLBI, NIDA, NIDCD, NLM, NIGMS, NIEHS, NINR, NIAID, NIDDK, NIBIB, NINDS, NCATS, NIA

07/14/2020

Not Applicable

04/06/2021

R41/R42

PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)

PAR-20-239

NIGMS

06/25/2020

Not Applicable

September 4, 2020; September 3, 2021; September 2, 2022

09/03/2022

R41/R42

Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (STTR) (R41/R42 Clinical Trial Not Allowed)

PAR-20-244

NIGMS

06/25/2020

Not Applicable

September 4, 2020; September 3, 2021; September 2 , 2022

09/03/2022

R43/R44

Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) (R43/R44 Clinical Trial Not Allowed)

RFA-HG-20-016

NHGRI

NCATS

03/19/2020

30 days prior to the application due date

June 24, 2020; March 9, 2021; February 4, 2022 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

02/05/2022

R43/R44

Novel Synthetic Nucleic Acid Technology Development (R43/R44)( Clinical Trial not allowed)

PAR-20-111

NINDS

NCCIH, NIDCR, NIAAA, NICHD, NIDA, NIA, NEI, OBSSR, NIMH

03/03/2020

30 days prior to the application due date

August 11, 2020, February 9, 2021,August 10, 2021,February 9, 2022,August 9, 2022, February 9, 2023 by 5:00 PM local time of applicant organization.

05/08/2023

U44

Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)

PAR-20-109

NCATS

NINDS, NIA, NIGMS, NIAID

02/06/2020

30 days prior to the application due date

Standard dates apply The first standard due date for this FOA is April 5, 2020

01/06/2022

R41/R42

Non-Viral Technologies for in vivo Delivery of Genome Editors (R41/R42 Clinical Trial Not Allowed)

PAR-20-098

NCATS

NIA, NIGMS, NIAID, NINDS

02/06/2020

30 days prior to the application due date

Standard dates apply The first standard due date for this FOA is April 5, 2020

01/06/2022

R43/R44

Non-Viral Technologies for in vivo Delivery of Genome Editors (R43/R44 Clinical Trial Not Allowed)

PA-20-025

NIMH

NIEHS, NIGMS, NCATS, NIDCR, NIDA, NEI, NHGRI

01/07/2020

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2023

R41/R42

Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed)

PA-20-047

NIMH

NCATS, NCI, NEI, NHGRI, NIDA, NIDCR, NIEHS, NIGMS

01/07/2020

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

01/06/2023

R43/R44

Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed)

RFA-NS-20-009

NINDS

NICHD, NIBIB, NIMH, NIDDK, NIAAA, NCCIH, ORIP, NIA, NIAMS, NHLBI, NIGMS, NCI, NIMHD, NCATS, NEI, NINR, NIDCR, NLM

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R41/R42

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)

RFA-NS-20-008

NINDS

NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R41/R42

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required)

RFA-NS-20-010

NINDS

NIAAA, NIA, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NIMH, NINR, NHLBI, NEI

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R43/R44

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)

RFA-NS-20-011

NINDS

NIAAA, NIA, NIAMS, NCCIH, NCI, NIDDK, NIGMS, NICHD, NIBIB, NIMHD, NLM, NIMH, NINR, NCATS, ORIP, NHLBI, NIDCR, NEI

10/04/2019

30 days prior to the application due date

January 8, 2020, April 7, 2020, September 9, 2020, January 6, 2021, April 6, 2021, September 8, 2021, January 6, 2022, April 6, 2022, and September 8, 2022

09/09/2022

R43/R44

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)

PAS-19-316

NIA

NINDS

07/18/2019

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity are due on these dates. The first standard application due date for this FOA is September 5, 2019.

09/07/2022

R43/R44

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)

PAS-19-317

NIA

NINDS

07/18/2019

Not Applicable

09/07/2022

R41/R42

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)

PAR-19-266

ORIP

05/02/2019

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization.

04/06/2021

R41/R42

Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)

PAR-19-265

ORIP

05/02/2019

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization. by 5:00 PM local time of applicant organization. All types of applications allowed for this funding opportunity announcement are due on these dates.

04/06/2021

R43/R44

Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)

RFA-DA-19-020

NIDA

NCATS

12/10/2018

30 days prior to the application due date

January 8, 2019, April 9, 2019, September 8, 2019, April 9, 2020, September 8, 2020, April 9, 2021, September 8, 2021, by 5:00 PM local time of applicant organization. No late applications will be accepted. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/09/2021

R41/R42

HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R41/R42 - Clinical Trial Optional)

RFA-DA-19-019

NIDA

NCATS

12/10/2018

30 days prior to application due date

09/09/2021

R43/R44

HEAL Initiative: Americas Startups and Small Businesses Build Technologies to Stop the Opioid Epidemic (R43/R44 - Clinical Trial Optional)

PA-19-076

NIDCR

11/26/2018

Not Applicable

Standard dates apply

01/06/2022

R43/R44

Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44 Clinical Trial Not Allowed)

PA-19-075

NIDCR

11/26/2018

Not Applicable

Standard dates apply

01/06/2022

R41/R42

Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42 Clinical Trial Not Allowed)

PAR-19-061

NHGRI

11/08/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

09/06/2021

R43/R44

Investigator Initiated Research in Computational Genomics and Data Science (R43/R44 Clinical Trial Not Allowed)

PA-19-043

NHGRI

10/31/2018

30 days prior to the application due date

09/06/2021

R43/R44

Novel Approaches for Relating Genetic Variation to Function and Disease (R43/R44 Clinical Trial Not Allowed)

PA-19-033

NIDCR

NCATS, NCI, NHLBI, NIMH, NLM

10/24/2018

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R41/R42

Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R41/R42 Clinical Trial Not Allowed)

PA-19-034

NIDCR

NCATS, NCI, NHLBI, NIMH, NLM

10/24/2018

Not Applicable

Standard dates apply by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R43/R44

Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R43/R44 Clinical Trial Not Allowed)

PA-19-022

NIDCR

10/09/2018

Not Applicable

Standard dates apply

09/06/2021

R43/R44

Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R43/R44 Clinical Trial Not Allowed)

PA-19-021

NIDCR

10/09/2018

Not Applicable

Standard dates apply

09/06/2021

R41/R42

Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42 Clinical Trial Not Allowed)

PA-18-927

NIMH

09/19/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R41/R42

Innovative Technologies for HIV Behavioral and Social Science Research (R41/R42 Clinical Trial Optional)

PA-18-928

NIMH

09/19/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates.

09/06/2021

R43/R44

Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)

PA-18-870

NIMH

NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NINDS

07/24/2018

Not Applicable

05/07/2021

R41/R42

BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42 - Clinical Trials Not Allowed)

PA-18-871

NIMH

NEI, NICHD, NIAAA, NIDA, NCCIH, NIBIB, NINDS, NIDCD

07/24/2018

Not Applicable

05/07/2021

R43/R44

BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR) (R43/R44 - Clinical Trial Not Allowed)

PA-18-819

NIMH

06/06/2018

30 days prior to the application due date

04/06/2021

R43/R44

Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional)

PA-18-816

NIGMS

06/05/2018

Not Applicable

04/06/2021

R41/R42

Better Defining Growth Medium to Improve Reproducibility of Cell Culture (STTR) (R41/R42 - Clinical Trial Not Allowed)

PA-18-815

NIGMS

06/05/2018

Not Applicable

04/06/2021

R43/R44

Better Defining Growth Medium to Improve Reproducibility of Cell Culture (SBIR) (R43/R44 - Clinical Trial Not Allowed)

PA-18-786

NIAAA

05/15/2018

Not Applicable

Standard dates apply , by 5:00 PM local time of applicant organization. *** Note new SBIR/STTR Standard Due Dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

04/06/2021

R43/R44

Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional)

PA-18-785

NIAAA

05/15/2018

Not Applicable

04/06/2021

R41/R42

Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional)

PA-18-709

NIMH

03/15/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

09/06/2021

R41/R42

Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42)-Clinical Trial Not Allowed

PA-18-708

NIMH

03/15/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

09/06/2021

R43/R44

Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R43/R44 Clinical Trial Not Allowed)

PA-18-705

NINDS

NCI, NEI, NIA, NIAAA, NIDA, NIDCR, NINR

03/06/2018

Not Applicable

04/06/2021

R43/R44

SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)

PAR-18-665

NINDS

02/15/2018

30 days prior to the application due date

April 16th then Standard dates apply , by 5:00 PM local time of applicant organization.

04/06/2021

R44

NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional)

PAR-18-628

NINDS

02/05/2018

Not Applicable

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2021

U44

NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)

PAR-18-617

NINDS

02/01/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

04/06/2021

R42

NINDS Exploratory Clinical Trials for Small Business (R42) - Clinical Trial Required

PAR-18-618

NINDS

02/01/2018

30 days prior to the application due date

Standard dates apply , by 5:00 PM local time of applicant organization.

04/06/2021

R44

NINDS Exploratory Clinical Trials for Small Business (R44) - Clinical Trial Required

PAR-18-578

NIAAA

01/12/2018

30 days prior to the application due date

March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020; March 25, 2021, by 5:00 PM local time of applicant organization.

03/26/2021

U44

Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (U44 - Clinical Trial Optional)

PAR-18-580

NIAAA

01/12/2018

30 days before the due date

March 27, 2018; December 4, 2018; March 27, 2019; December 4, 2019; March 27, 2020; December 4, 2020, by 5:00 PM local time of applicant organization.

03/26/2021

UT2

Investigational New Drug (IND)-enabling Development of Medications to Treat Alcohol Use disorder and Alcohol-related disorders (UT2 -Clinical Trial Optional)

PA-18-579

NIMH

01/12/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2021

R41/R42

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)

PA-18-566

NIMH

01/12/2018

30 days prior to the application due date

Standard dates apply, by 5:00 PM local time of applicant organization.

04/06/2021

R43/R44

Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44 Clinical Trial Optional)

PA-18-567

NIMH

01/09/2018

Not Applicable

04/06/2021

R44

Competing Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44 Clinical Trial Optional)

PAR-18-563

NINDS

01/09/2018

Not applicable

Standard dates apply , by 5:00 PM local time of applicant organization.

04/06/2021

U44

NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44 - Clinical Trials Optional)

RFA-NS-18-022

NINDS

NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NIMH

12/21/2017

30 days prior to the receipt date

February 23, 2018, June 21, 2018, October 22, 2018, February 21, 2019, June 21, 2019, October 21, 2019, February 21, 2020, June 22, 2020, October 21, 2020, by 5:00 PM local time of applicant organization.

02/23/2021

U44

BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)

PAR-18-543

NINDS

12/20/2017

Not Applicable

February 20, 2018, July 18, 2018, February 13, 2019, July 18, 2019, February 13, 2020, July 20, 2020), and February 12, 2021 by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

05/08/2021

U44

CREATE Bio Development Track: Preclinical and Early-Phase Clinical Development for Biologics (U44 SBIR- Clinical Trial Optional)

RFA-NS-18-012

NINDS

11/08/2017

30 days prior to the receipt date

February 21, 2018; June 21, 2018; October 22, 2018; February 21, 2019; June 21, 2019; October 21, 2019; February 21, 2020; June 22, 2020; and October 21, 2020 , February 22, 2021 by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

02/23/2021

U44

Translational Neural Devices (U44 - Clinical Trial Required)

PAR-17-457

NINDS

08/14/2017

Not Applicable

February 13, 2018; July 18, 2018; February 13, 2019; July 18, 2019; February 13, 2020; and July 20, 2020 , February 12, 2021 by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

05/08/2021

U44

NINDS CREATE Bio Optimization Track for Biologics (U44)

Targeted SBIR/STTR Funding Announcements

SBIR and STTR Omnibus Solicitations (Parent Announcements)

SBIR and STTR Funding Opportunities (69 Records - Sorted by Release Date)