3-Step Application Process

The NIH SBIR/STTR program has a comprehensive suite of resources to help small businesses submit their application successfully. Outlined below are a few resources to help your company move from an idea to commercialization:

Step #1: Develop an Innovative Idea

Make sure that your value proposition is relevant to NIDA's programmatic priorities and overall interests

Step #2: Complete 6 Registrations Prior to Application Submission

The registration process alone may take six to eight weeks, so it's important to start early. All registrations must be completed prior to the application being submitted.

Video tutorial which breaks down the SF424 (R&R) SBIR/STTR application page by page

  • Dun and Bradstreet Universal Numbering System (DUNSexit disclaimer icon)

  • Employer Identification Number (EIN)

  • System for Award Management (SAM)

  • (Register with

  • NIH's Electronic Research Administration System (eRA)

  • Small Business Administration Company Registry (SBA)

Step #3: Write a Strong Application and Apply for Funding

To apply for an SBIR or STTR grant, read through the PA Omnibus Solicitation and submit an application.

Need some help with completing the application? NIDA has a number of resources that can help (Application Resources).